SAB4504044

Anti-phospho-Myosin regulatory light chain 2 (pSer¹⁸) antibody produced in rabbit

affinity isolated antibody

• Sinónimos: Anti-CMH10, Anti-MFM12, Anti-MLC-2s/v, Anti-MLC2
• Código UNSPSC: 12352203
• NACRES: NA.41

Propiedades

• origen biológico: rabbit
• conjugado: unconjugated
• forma del anticuerpo: affinity isolated antibody
• tipo de anticuerpo: primary antibodies
• clon: polyclonal
• formulario: buffered aqueous solution
• mol peso: antigen 19 kDa
• reactividad de especies: human, rat, mouse
• concentración: ~1 mg/mL
• técnicas: ELISA: 1:20000; immunofluorescence: 1:100-1:500; immunohistochemistry: 1:50-1:100; western blot: 1:500-1:1000
• Nº de acceso NCBI: P24844
• Nº de acceso UniProt: P10916
• Condiciones de envío: wet ice
• temp. de almacenamiento: −20°C
• modificación del objetivo postraduccional: phosphorylation (pSer18)
• Información sobre el gen: human ... MYL2(4633)

Descripción

Descripción general

MYL2 (myosin light chain 2) encodes a myosin regulatory light chain (MLC-2V). It is made of two heavy chains, two essential light chains and two regulatory light chains. It is located on human chromosome 12q24.

Inmunógeno

The antiserum was produced against synthesized peptide derived from human Myosin regulatory light chain 2 around the phosphorylation site of Ser18.

Immunogen Range: 3-52

Acciones bioquímicas o fisiológicas

MYL2 (myosin light chain 2) helps to convert energy from ATP hydrolysis into mechanical force. This gene also plays a major role in the growth and progression of chronic HF (heart failure). Mutation in MYL2 gene result in infantile type I muscle fibre disease and cardiomyopathy.

Características y beneficios

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Forma física

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids
• Clase de riesgo para el agua (WGK): WGK 1
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable