SAB4503615

Anti-EDG5 antibody produced in rabbit

affinity isolated antibody

• Sinónimos: Endothelial differentiation G-protein coupled receptor 5, S1P receptor Edg-5, S1P2, Sphingosine 1-phosphate receptor 2, Sphingosine 1-phosphate receptor Edg-5
• Número MDL: MFCD02686109
• Código UNSPSC: 12352203
• NACRES: NA.41

Propiedades

• origen biológico: rabbit
• Nivel de calidad: 100
• conjugado: unconjugated
• forma del anticuerpo: affinity isolated antibody
• tipo de anticuerpo: primary antibodies
• clon: polyclonal
• formulario: buffered aqueous solution
• mol peso: antigen 38 kDa
• reactividad de especies: rat, human, mouse
• concentración: ~1 mg/mL
• técnicas: ELISA: 1:40000; western blot: 1:500-1:1000
• Nº de acceso NCBI: O95136
• Nº de acceso UniProt: O95136
• Condiciones de envío: wet ice
• temp. de almacenamiento: −20°C
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: human ... S1PR2(9294)

Descripción

Descripción general

Anti-EDG5 Antibody detects endogenous levels of total EDG5 protein.
EDG5/ S1PR2 (sphingosine-1-phosphate receptor 2), a pleiotropic lipid mediator is abundantly expressed in most of the tissues. S1PR2 codes for a 353 amino acid sphingosine-1-phosphate receptor 2 and is located on human chromosome 19p13.2.

Inmunógeno

The antiserum was produced against synthesized peptide derived from human EDG5.

Immunogen Range: 261-310

Acciones bioquímicas o fisiológicas

In NB (neuroblastoma), EDG5/ S1PR2 (sphingosine-1-phosphate receptor 2) helps in the expression of S1P-induced vascular endothelial growth factor. It promotes the Rho/Rho-kinase pathway. S1PR2 participates in S1P-induced platelet aggregation. S1PR2 is essential for normal auditory function as it is a part of the sphingosine-1-phosphate signaling (S1P) pathway.

Características y beneficios

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Forma física

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids
• Clase de riesgo para el agua (WGK): nwg
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable