SAB4503250

Anti-CAMK2 antibody produced in rabbit

affinity isolated antibody

• Sinónimos: CAMK2A, CaM-kinase II α chain, CaMK-II α subunit, CaMKII-α, Calcium/calmodulin-dependent protein kinase type II α chain
• Código UNSPSC: 12352203
• NACRES: NA.41

Propiedades

• origen biológico: rabbit
• Nivel de calidad: 100
• conjugado: unconjugated
• forma del anticuerpo: affinity isolated antibody
• tipo de anticuerpo: primary antibodies
• clon: polyclonal
• Formulario: buffered aqueous solution
• mol peso: antigen 54 kDa
• reactividad de especies: rat, mouse, human
• concentración: ~1 mg/mL
• técnicas: ELISA: 1:10000; immunofluorescence: 1:100-1:500; immunohistochemistry: 1:50-1:100; western blot: 1:500-1:1000
• Nº de acceso NCBI: Q9UQM7
• Nº de acceso UniProt: Q13557
• Condiciones de envío: wet ice
• temp. de almacenamiento: −20°C
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: human ... CAMK2A(815)

Descripción

Descripción general

Anti-CAMK2 Antibody detects endogenous levels of total CAMK2 protein.

Calcium/calmodulin dependent protein kinase II α (CAMK2) is a calcium-activated serine/threonine kinase. The gene is located on human chromosome 5q32. CAMK2 is mainly expressed in the central nervous system. It consists of a kinase domain, a regulatory domain and an association domain.

Inmunógeno

The antiserum was produced against synthesized peptide derived from human CaMK2 alpha/delta.

Immunogen Range: 256-305

Acciones bioquímicas o fisiológicas

Calcium/calmodulin dependent protein kinase II α (CAMK2) is essential for long-term potentiation (LTP) and spatial memory. It regulates synaptic plasticity. Dysfunction in this gene is associated with schizophrenia, epilepsy and autism spectrum disorders.

Calmodulin dependent protein kinase II complex δ (CAMK2D) modulates the functions of ion channels and Ca²⁺ handling proteins. It also regulates the phosphorylation and acetylation of histones. It has been shown to be overexpressed in the myocardium of diabetic patients.

Características y beneficios

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Forma física

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids
• Clase de riesgo para el agua (WGK): nwg
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable