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Merck
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SAB4503057

Sigma-Aldrich

Anti-PGP9.5 antibody produced in rabbit

affinity isolated antibody

Sinónimos:

UCH-L1, neuron cytoplasmic protein 9.5, ubiquitin carboxyl-terminal hydrolase isozyme L1, ubiquitin thiolesterase L1

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About This Item

Código UNSPSC:
12352203
NACRES:
NA.41

origen biológico

rabbit

Nivel de calidad

100

conjugado

unconjugated

forma del anticuerpo

affinity isolated antibody

tipo de anticuerpo

primary antibodies

clon

polyclonal

formulario

buffered aqueous solution

mol peso

antigen 24 kDa

reactividad de especies

mouse, rat, human

concentración

~1 mg/mL

técnicas

ELISA: 1:5000
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000

Nº de acceso UniProt

P09936

Condiciones de envío

wet ice

temp. de almacenamiento

−20°C

modificación del objetivo postraduccional

unmodified

Información sobre el gen

human ... UCHL1(7345)

Descripción general

Anti-PGP9.5 Antibody detects endogenous levels of total PGP9.5 protein.
The PGP9.5 (protein gene product 9.5) gene is mapped to human chromosome 4p13. The encoded protein is predominantly expressed in the brain.

Inmunógeno

The antiserum was produced against synthesized peptide derived from human PGP9.5.

Immunogen Range: 171-220

Características y beneficios

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Forma física

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Código de clase de almacenamiento

12 - Non Combustible Liquids

Clase de riesgo para el agua (WGK)

nwg

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Manasi Sayilekshmy et al.
Scientific reports, 9(1), 5361-5361 (2019-03-31)
Mounting evidence from animal studies suggests a role of the nervous system in bone physiology. However, little is known about the nerve fiber localization to human bone compartments and bone surface events. This study reveals the density and distribution of
Iris Shinkarevsky Fleitman et al.
Muscle & nerve, 61(6), 791-796 (2020-03-07)
Small-fiber neuropathy is rare in children. It has been associated with several autoimmune disorders, but there are no reports of an autoinflammatory etiology. The data of four children/adolescents presenting with erythromelalgia and neuropathic pain from 2014 to 2019 were collected
Mitochondria: The Next (Neurode)Generation
Schon EA, et al.
Neuron, 70(6), 1033-1053 (2011)
Familial Mutations and Post-translational Modifications of UCH-L1 in Parkinson's Disease and Neurodegenerative Disorders.
C Lee YT, et al.
Current Protein and Peptide Science, 18(7), 733-745 (2017)
Rie B Hansen et al.
Frontiers in pain research (Lausanne, Switzerland), 3, 887747-887747 (2022-06-18)
Pain is a common complication for patients with metastatic bone disease. Animal models suggest that the pain, in part, is driven by pathological sprouting and reorganization of the nerve fibers innervating the bone. Here, we investigate how these findings translate
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