SAB4502609

Anti-NF-κB p65 antibody produced in rabbit

affinity isolated antibody

• Sinónimos: NFKB3, RELA, TF65, nuclear factor NF-κ-B p65 subunit, p65
• Número MDL: MFCD00802848
• Código UNSPSC: 12352203
• NACRES: NA.41

Propiedades

• origen biológico: rabbit
• Nivel de calidad: 100
• conjugado: unconjugated
• forma del anticuerpo: affinity isolated antibody
• tipo de anticuerpo: primary antibodies
• clon: polyclonal
• Formulario: buffered aqueous solution
• mol peso: antigen 60 kDa
• reactividad de especies: human, mouse
• concentración: ~1 mg/mL
• técnicas: ELISA: 1:20000; western blot: 1:500-1:1000
• Nº de acceso NCBI: Q04206
• Nº de acceso UniProt: Q04206
• Condiciones de envío: wet ice
• temp. de almacenamiento: −20°C
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: human ... RELA(5970)

Descripción

Descripción general

Anti-NF-κB p65 antibody detects endogenous levels of total NF-κB p65 protein.

The NF-κB p65 (nuclear factor κ-light-chain-enhancer of activated B cells p65) gene is mapped to human chromosome 11q13.1. It codes for a transcription factor, a subunit of NF-κB.

Inmunógeno

The antiserum was produced against synthesized peptide derived from human NF-kappaB p65.

Immunogen Range: 278-327

Aplicación

Anti-NF-κB p65 antibody produced in rabbit has been used in western blot analysis.

Acciones bioquímicas o fisiológicas

NF-κB p65 (nuclear factor κ-light-chain-enhancer of activated B cells p65) is associated with many fibrotic diseases such as liver fibrosis and cardiac fibrosis. Cell proliferation, inflammation, and apoptosis are some of the processes mediated by NF-κB p65. Dysregulation of the gene results in chronic inflammatory diseases, autoimmune disorders and cancer. NF-κB p65 plays an important role in NF-κB signaling.

Características y beneficios

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Forma física

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids
• Clase de riesgo para el agua (WGK): nwg
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable