SAB4501900

Anti-MMP-13 antibody produced in rabbit

affinity isolated antibody

• Sinónimos: Collagenase 3, MMP-13, MMP13, Matrix metalloproteinase-13
• Número MDL: MFCD03455405
• Código UNSPSC: 12352203
• NACRES: NA.41

Propiedades

• origen biológico: rabbit
• Nivel de calidad: 100
• conjugado: unconjugated
• forma del anticuerpo: affinity isolated antibody
• tipo de anticuerpo: primary antibodies
• clon: polyclonal
• Formulario: buffered aqueous solution
• mol peso: antigen 53 kDa
• reactividad de especies: human
• concentración: ~1 mg/mL
• técnicas: ELISA: 1:40000; immunofluorescence: 1:100-1:500; immunohistochemistry: 1:50-1:100; western blot: 1:500-1:1000
• Nº de acceso NCBI: P45452
• Nº de acceso UniProt: P45452
• Condiciones de envío: wet ice
• temp. de almacenamiento: −20°C
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: human ... MMP13(4322)

Descripción

Descripción general

Anti-MMP-13 Antibody detects endogenous levels of total MMP-13 protein.

Matrix metalloproteinases (MMPs) are a class of extra-cellular and membrane-bound proteases. MMP13 (matrix metallopeptidase 13) is mapped to human chromosome 11q14.3–23.2.

Inmunógeno

The antiserum was produced against synthesized peptide derived from human MMP-13.

Immunogen Range: 10-59

Acciones bioquímicas o fisiológicas

MMP13 (matrix metallopeptidase 13) participates in tissue remodeling, inflammation, cytokine secretion and activation. It also plays an important role in acute lung injury, viral infections and chronic obstructive pulmonary disease. Mutation in MMP13 results in spondyloepimetaphyseal dysplasia, missouri type (SEMDMO).

Características y beneficios

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Forma física

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids
• Clase de riesgo para el agua (WGK): nwg
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable