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Key Documents

SAB4501465

Sigma-Aldrich

Anti-HSP10 antibody produced in rabbit

affinity isolated antibody

Sinónimos:

CHAPERONIN 10 HOMOLOG, GroES HOMOLOG, HEAT-SHOCK 10-KD PROTEIN

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About This Item

Número MDL:
Código UNSPSC:
12352203
NACRES:
NA.41

origen biológico

rabbit

conjugado

unconjugated

forma del anticuerpo

affinity isolated antibody

tipo de anticuerpo

primary antibodies

clon

polyclonal

formulario

buffered aqueous solution

mol peso

antigen 10 kDa

reactividad de especies

rat, mouse, human

concentración

~1 mg/mL

técnicas

ELISA: 1:10000
immunofluorescence: 1:100-1:500
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000

Nº de acceso NCBI

Nº de acceso UniProt

Condiciones de envío

wet ice

temp. de almacenamiento

−20°C

modificación del objetivo postraduccional

unmodified

Información sobre el gen

human ... HSPE1(3336)

Categorías relacionadas

Descripción general

Anti-HSP10 Antibody detects endogenous levels of total HSP10 protein.
HSP10 (heat shock protein family E member 1) is a molecular chaperone protein, located in mitochondria. It is encoded by HSPE1 (heat shock protein family E member 1) gene, that is located on human chromosome 2q33.1.

Inmunógeno

The antiserum was produced against synthesized peptide derived from human HSP10.

Immunogen Range: 51-100

Aplicación

Anti-HSP10 antibody has been used in microarray and western blotting.

Acciones bioquímicas o fisiológicas

Overexpression of HSP10 (heat shock protein family E member 1) protein blocks apoptosis and results in poor prognosis of astrocytoma. It participates in immunomodulation and tumor progression.

Características y beneficios

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Forma física

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Código de clase de almacenamiento

10 - Combustible liquids

Clase de riesgo para el agua (WGK)

nwg

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable


Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Visite la Librería de documentos

Hsp10 nuclear localization and changes in lung cells response to cigarette smoke suggest novel roles for this chaperonin.
Corrao S, et al.
Open Biology, 4(10) (2014)
Juha J Hulmi et al.
Free radical biology & medicine, 99, 308-322 (2016-10-23)
Protein homeostasis in cells, proteostasis, is maintained through several integrated processes and pathways and its dysregulation may mediate pathology in many diseases including Duchenne muscular dystrophy (DMD). Oxidative stress, heat shock proteins, endoplasmic reticulum (ER) stress and its response, i.e.
Effects of muscular dystrophy, exercise and blocking activin receptor IIB ligands on the unfolded protein response and oxidative stress.
Hulmi JJ, et al.
Free Radical Biology & Medicine, 99, 308-322 (2016)
Effects of intrinsic aerobic capacity, aging and voluntary running on skeletal muscle sirtuins and heat shock proteins.
Karvinen S, et al.
Experimental Gerontology, 79, 46-54 (2016)
Elevated expression of HSP10 protein inhibits apoptosis and associates with poor prognosis of astrocytoma.
Fan W, et al.
PLoS ONE, 12(10) (2017)

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