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SAB4300599

Sigma-Aldrich

Anti-MET (Ab-1003) antibody produced in rabbit

affinity isolated antibody

Sinónimos:

Anti-AUTS9 antibody produced in rabbit, Anti-HGFR antibody produced in rabbit, Anti-RCCP2 antibody produced in rabbit, Anti-c-Met antibody produced in rabbit, Anti-met proto-oncogene (hepatocyte growth factor receptor) antibody produced in rabbit

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About This Item

Número MDL:
Código UNSPSC:
12352203
NACRES:
NA.41

origen biológico

rabbit

Nivel de calidad

conjugado

unconjugated

forma del anticuerpo

affinity isolated antibody

tipo de anticuerpo

primary antibodies

clon

polyclonal

formulario

buffered aqueous solution

mol peso

~156 kDa

reactividad de especies

rat, human, mouse

concentración

1 mg/mL

técnicas

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100
western blot: 1:500-1:1000

isotipo

IgG

secuencia del inmunógeno

(V-D-Y-R-A)

Nº de acceso NCBI

Nº de acceso UniProt

Condiciones de envío

wet ice

temp. de almacenamiento

−20°C

modificación del objetivo postraduccional

unmodified

Información sobre el gen

human ... MET(4233)

Descripción general

MET/c-Met (mesenchymal-epithelial transition factor) is a tyrosine kinase receptor , that is located on chromosome 7q31.

Inmunógeno

Peptide sequence around aa. 1001-1005 (V-D-Y-R-A), according to the protein MET.

Acciones bioquímicas o fisiológicas

MET/c-Met (mesenchymal-epithelial transition factor) controls several biological processes like cell scattering, survival, proliferation, migration and c-MET signaling.(31)

Características y beneficios

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Descripción de destino

Receptor for hepatocyte growth factor and scatter factor. Has a tyrosine-protein kinase activity. Functions in cell proliferation, scattering, morphogenesis and survival.

Forma física

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Código de clase de almacenamiento

10 - Combustible liquids

Clase de riesgo para el agua (WGK)

WGK 1

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable


Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Visite la Librería de documentos

The c-Met receptor: Implication for targeted therapies in colorectal cancer
Safaie Qamsari E, et al.
Tumour Biology : the Journal of the International Society For Oncodevelopmental Biology and Medicine, 39(5) (2017)
Nayeon Lee et al.
Biochemistry and biophysics reports, 26, 100973-100973 (2021-03-16)
Hepatocyte growth factor (HGF) is a neurotrophic factor and its role in peripheral nerves has been relatively unknown. In this study, biological functions of HGF and its receptor c-met have been investigated in the context of regeneration of damaged peripheral
Kyeong Ryang Ko et al.
Scientific reports, 8(1), 8316-8316 (2018-05-31)
During the peripheral nerve regeneration process, a variety of neurotrophic factors play roles in nerve repair by acting on neuronal or non-neuronal cells. In this report, we investigated the role(s) of hepatocyte growth factor (HGF) and its receptor, c-met, in
Phase II study of the c-MET inhibitor tivantinib (ARQ 197) in patients with relapsed or relapsed/refractory multiple myeloma
Baljevic M, et al.
Annals of Hematology, 96(6), 977-985 (2017)
Phase II and biomarker study of the dual MET/VEGFR2 inhibitor foretinib in patients with papillary renal cell carcinoma
Choueiri TK, et al.
Journal of Clinical Oncology, 31(2), 181-186 (2013)

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