SAB4300155

Anti-phospho-HDAC4 (pSer⁶³²) antibody produced in rabbit

affinity isolated antibody

• Sinónimos: Anti-HA6116 antibody produced in rabbit, Anti-HD4 antibody produced in rabbit, Anti-HDAC-A antibody produced in rabbit, Anti-HDACA antibody produced in rabbit, Anti-histone deacetylase 4 antibody produced in rabbit
• Código UNSPSC: 12352203
• NACRES: NA.41

Propiedades

• origen biológico: rabbit
• Nivel de calidad: 100
• conjugado: unconjugated
• forma del anticuerpo: affinity isolated antibody
• tipo de anticuerpo: primary antibodies
• clon: polyclonal
• formulario: buffered aqueous solution
• mol peso: ~140 kDa
• reactividad de especies: mouse, rat, human
• concentración: 1 mg/mL
• técnicas: western blot: 1:500-1:1000
• isotipo: IgG
• secuencia del inmunógeno: (A-Q-SP-S-P)
• Nº de acceso NCBI: NP_006028.2
• Nº de acceso UniProt: P56524
• Condiciones de envío: wet ice
• temp. de almacenamiento: −20°C
• modificación del objetivo postraduccional: phosphorylation (pSer632)
• Información sobre el gen: human ... HDAC4(9759)

Descripción

Inmunógeno

Peptide sequence around phosphorylation site of serine 632 (A-Q-S(p)-S-P), according to the protein HDAC4.

Aplicación

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Western Blotting (1 paper)

Características y beneficios

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Descripción de destino

Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation via its interaction with the myocyte enhancer factors such as MEF2A, MEF2C and MEF2D.

Forma física

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids
• Clase de riesgo para el agua (WGK): WGK 1
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable