Saltar al contenido
Merck

SAB4200722

Sigma-Aldrich

Anti-Band 3 antibody, Mouse monoclonal

clone BIII-136, purified from hybridoma cell culture

Sinónimos:

AE 1, Anion exchange protein 1, Anion exchanger 1, Band 3 anion transport protein, Solute carrier family 4 member 1

Iniciar sesiónpara Ver la Fijación de precios por contrato y de la organización


About This Item

Código UNSPSC:
12352203
NACRES:
NA.46

origen biológico

mouse

Nivel de calidad

forma del anticuerpo

purified from hybridoma cell culture

tipo de anticuerpo

primary antibodies

clon

BIII-136, monoclonal

Formulario

buffered aqueous solution

reactividad de especies

human

concentración

~1 mg/mL

técnicas

immunoblotting: 2-4 μg/mL (human erythrocytes ghosts extract)
immunoprecipitation (IP): suitable

isotipo

IgG2a

Nº de acceso UniProt

Condiciones de envío

dry ice

temp. de almacenamiento

−20°C

modificación del objetivo postraduccional

unmodified

Información sobre el gen

human ... SLC4A1(6521)

Descripción general

Anti-Band 3 antibody, Mouse monoclonal (mouse IgG2a isotype) is derived from the BIII-136 hybridoma produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mouse immunized with glycophorin B purified from human erythrocytes.

Aplicación

Anti-Band 3 antibody, Mouse monoclonal may be used in immunoblotting and immunoprecipitation.

Acciones bioquímicas o fisiológicas

As a response to an oxidative stress, Band 3 protein forms clusters and clear damaged and aged RBCs from circulation. Enhanced band 3 protein clustering is implicated in RBC disorders such as hemolytic anemia, glucose-6-phosphate dehydrogenase (G6PD) deficiency, malaria and sickle-cell disease.

Forma física

Glycophorin B purified from human erythrocytes
Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

¿No encuentra el producto adecuado?  

Pruebe nuestro Herramienta de selección de productos.

Código de clase de almacenamiento

10 - Combustible liquids

Clase de riesgo para el agua (WGK)

WGK 1

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable


Elija entre una de las versiones más recientes:

Certificados de análisis (COA)

Lot/Batch Number

¿No ve la versión correcta?

Si necesita una versión concreta, puede buscar un certificado específico por el número de lote.

¿Ya tiene este producto?

Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.

Visite la Librería de documentos

Akihiro Moriyama et al.
Scientific reports, 5, 17427-17427 (2015-12-01)
Membrane proteins interact with membrane lipids for their structural stability and proper function. However, lipid-protein interactions are poorly understood at a molecular level especially in the live cell membrane, due to current limitations in methodology. Here, we report that amphiphilic
Kodjo Ayi et al.
Blood, 104(10), 3364-3371 (2004-07-29)
High frequency of erythrocyte (red blood cell [RBC]) genetic disorders such as sickle cell trait, thalassemia trait, homozygous hemoglobin C (Hb-C), and glucose-6-phosphate dehydrogenase (G6PD) deficiency in regions with high incidence of Plasmodium falciparum malaria and case-control studies support the
Changes in band 3 structure as determinants of erythrocyte integrity during storage and survival after transfusion.
Giel J C G M Bosman et al.
Blood transfusion = Trasfusione del sangue, 8 Suppl 3, s48-s52 (2010-07-08)
Changes in band 3 structure as determinants of erythrocyte integrity during storage and survival after transfusion
Bosman G, et al.
Blood Transfusion = Trasfusione del Sangue, 8(Suppl 3), s48-s48 (2010)
J R Pawloski et al.
Nature, 409(6820), 622-626 (2001-02-24)
Previous studies support a model in which the physiological O2 gradient is transduced by haemoglobin into the coordinate release from red blood cells of O2 and nitric oxide (NO)-derived vasoactivity to optimize oxygen delivery in the arterial periphery. But whereas

Nuestro equipo de científicos tiene experiencia en todas las áreas de investigación: Ciencias de la vida, Ciencia de los materiales, Síntesis química, Cromatografía, Analítica y muchas otras.

Póngase en contacto con el Servicio técnico