SAB4200519

Anti-GLUT1 (C-terminal) antibody produced in rabbit

~1.0 mg/mL, affinity isolated antibody

• Sinónimos: Anti-SLC2A1, Anti-member 1, Anti-solute carrier family 2 (facilitated glucose transporter)
• Código UNSPSC: 12352203
• NACRES: NA.41

Propiedades

• origen biológico: rabbit
• Nivel de calidad: 200
• conjugado: unconjugated
• forma del anticuerpo: affinity isolated antibody
• tipo de anticuerpo: primary antibodies
• clon: polyclonal
• Formulario: buffered aqueous solution
• mol peso: antigen ~55-70 kDa
• reactividad de especies: mouse, rat, human
• concentración: ~1.0 mg/mL
• técnicas: western blot: 0.5-1.0 μg/mL using rat spinal cord extracts (S1 fraction)
• Nº de acceso UniProt: P11166
• Condiciones de envío: dry ice
• temp. de almacenamiento: −20°C
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: human ... SLC2A1(6513) ; mouse ... Slc2a1(20525) ; rat ... Slc2a1(24778)

Descripción

Descripción general

Glucose transporter 1 (GLUT1, SLC2A1) belongs to the family of glucose transporters (GLUTs). It is localized to the membrane and is highly expressed in the brain and spinal cord, with a relative high density in the cerebellum. The vascular form of GLUT1 is mainly localized in endothelial cells of blood vessels.

Inmunógeno

peptide corresponding to a sequence at the C-terminus of human GLUT1, conjugated to KLH. The corresponding sequence is identical in rat and mouse GLUT1.

Aplicación

Anti-GLUT1 (C-terminal) antibody produced in rabbit has been used in immunoblotting.

Acciones bioquímicas o fisiológicas

GLUT1 is the main glucose transporter in the blood-brain barrier (BBB), which regulates basal glucose levels. Increased expression of GLUT1 is associated with cell growth and in malignant transformation.

Forma física

solution in 0.01 M phos­phate buffered saline, pH 7.4, containing 15 mM sodium azide.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable