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Merck
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SAB3501044

Sigma-Aldrich

Anti-TFEB antibody produced in rabbit

affinity isolated antibody

Sinónimos:

Anti-ALPHATFEB, Anti-BHLHE35, Anti-TCFEB

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About This Item

Código UNSPSC:
12352203
NACRES:
NA.41

origen biológico

rabbit

Nivel de calidad

100

conjugado

unconjugated

forma del anticuerpo

affinity isolated antibody

tipo de anticuerpo

primary antibodies

clon

polyclonal

formulario

buffered aqueous solution

reactividad de especies

human

concentración

1 mg/mL

técnicas

ELISA: suitable
immunofluorescence: suitable
immunohistochemistry: suitable

Nº de acceso NCBI

NP_009093

Nº de acceso UniProt

P19484

Condiciones de envío

wet ice

temp. de almacenamiento

−20°C

modificación del objetivo postraduccional

unmodified

Información sobre el gen

human ... TFEB(7942)

Inmunógeno

Antibody was raised against a 16 amino acid peptide near the carboxy terminus of human TFEB.

Características y beneficios

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Forma física

Supplied at 1 mg/mL in PBS with 0.02% sodim azide.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Código de clase de almacenamiento

10 - Combustible liquids

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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C S Carr et al.
Molecular and cellular biology, 10(8), 4384-4388 (1990-08-01)
A human cDNA encoding a novel protein in the helix-loop-helix family has been isolated by screening a bacteriophage expression library with a probe containing the binding site for major late transcription factor. The protein encoded by this cDNA, TFEB, probably
Marco Sardiello et al.
Science (New York, N.Y.), 325(5939), 473-477 (2009-06-27)
Lysosomes are organelles central to degradation and recycling processes in animal cells. Whether lysosomal activity is coordinated to respond to cellular needs remains unclear. We found that most lysosomal genes exhibit coordinated transcriptional behavior and are regulated by the transcription
Ian J Davis et al.
Proceedings of the National Academy of Sciences of the United States of America, 100(10), 6051-6056 (2003-04-30)
MITF, TFE3, TFEB, and TFEC comprise a transcription factor family (MiT) that regulates key developmental pathways in several cell lineages. Like MYC, MiT members are basic helix-loop-helix-leucine zipper transcription factors. MiT members share virtually perfect homology in their DNA binding
Randall Logan et al.
Journal of pharmaceutical sciences, 103(10), 3287-3296 (2014-07-22)
Many weakly basic amine-containing drugs are known to be extensively sequestered in acidic lysosomes by an ion trapping-type mechanism. The entrapment of drugs in lysosomes has been shown to influence drug activity, cancer cell selectivity, and pharmacokinetics and can cause

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