SAB3500514

Anti-ZEB1 antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

• Sinónimos: Anti-AREB6, Anti-BZP, Anti-TCF8, Anti-Zinc finger E-box binding homeobox 1
• Código UNSPSC: 12352203
• NACRES: NA.41

Propiedades

• origen biológico: rabbit
• conjugado: unconjugated
• forma del anticuerpo: affinity isolated antibody
• tipo de anticuerpo: primary antibodies
• clon: polyclonal
• formulario: buffered aqueous solution
• mol peso: predicted mol wt 124 kDa
• reactividad de especies: human
• técnicas: immunocytochemistry: suitable; immunofluorescence: suitable; immunohistochemistry: suitable; indirect ELISA: suitable; western blot: suitable
• Nº de acceso NCBI: CAI12550
• Nº de acceso UniProt: P37275
• Condiciones de envío: dry ice
• temp. de almacenamiento: −20°C
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: human ... ZEB1(6935)

Descripción

Descripción general

Zinc finger E-box-binding homeobox 1 (ZEB1) is an EMT (epithelial-mesenchymal transition) transcription factor. The gene encoding this protein is localized on human chromosome 10p11.2.

Inmunógeno

ZEB1 antibody was raised against a 15 amino acid peptide near the center of human ZEB1.

The immunogen is located within amino acids 530 - 580 of ZEB1.

Aplicación

Anti-ZEB1 antibody produced in rabbit has been used in western blotting.

Acciones bioquímicas o fisiológicas

Zinc finger E-box-binding homeobox 1 (ZEB1) controls the expression of E-cadherin as a repressor. It plays an important role in tumor invasion and metastasis. Epigenetic suppression of ZEB1 might be a useful tool for overcoming drug resistance in human breast cancer. Mutations in this gene are associated with posterior polymorphous corneal dystrophy and Fuchs′ endothelial corneal dystrophy (FECD6).

Características y beneficios

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Ligadura / enlace

The action of this antibody can be blocked using blocking peptide SBP3500514.

Forma física

Supplied in PBS with 0.02% sodium azide.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable