SAB3500178

Anti-LXR-A antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

• Sinónimos: Anti-LXRA, Anti-Liver X receptor A, Anti-NR1H3, Anti-Nuclear receptor subfamily 1 group H member 3
• Código UNSPSC: 12352203
• NACRES: NA.41

Propiedades

• origen biológico: rabbit
• conjugado: unconjugated
• forma del anticuerpo: affinity isolated antibody
• tipo de anticuerpo: primary antibodies
• clon: polyclonal
• formulario: buffered aqueous solution
• mol peso: predicted mol wt 44-49 kDa
• reactividad de especies: rat, human, mouse
• técnicas: immunofluorescence: suitable; immunohistochemistry: suitable; indirect ELISA: suitable; western blot: suitable
• Nº de acceso NCBI: NP_005684
• Nº de acceso UniProt: Q13133
• Condiciones de envío: dry ice
• temp. de almacenamiento: −20°C
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: human ... NR1H3(10062)

Descripción

Descripción general

The gene LXR α (liver X receptor α) is a member of LXRs that belong to the nuclear receptor superfamily. The encoded protein is expressed predominantly in macrophages, liver, intestine, kidney, lung and adipose tissue. The gene is mapped to human chromosome 11p11.2. The protein contains a DNA-binding domain that requires the ligand-binding domain to heterodimerize with a retinoid X receptor partner for its DNA-binding activity.

Inmunógeno

LXR-A antibody was raised against a 15 amino acid peptide from near the amino terminus human LXR-A.

Acciones bioquímicas o fisiológicas

The gene LXR α (liver X receptor α) encodes a protein that plays an important role in the control of cholesterol homeostasis. LXRs have been found to regulate inflammatory response in macrophages. They are also involved in the regulation of cell proliferation.

Características y beneficios

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Ligadura / enlace

The action of this antibody can be blocked using blocking peptide SBP3500178.

Forma física

Supplied in PBS with 0.02% sodium azide.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids
• Clase de riesgo para el agua (WGK): WGK 2
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable