SAB2702341

Monoclonal Anti-ARID1A antibody produced in mouse

clone GT3611, affinity isolated antibody

• Sinónimos: B120, BAF250, BAF250a, BM029
• Código UNSPSC: 12352203
• NACRES: NA.41
• conjugado: unconjugated
• application: IF; IHC; WB
• clon: GT3611, monoclonal
• reactividad de especies: human, mouse
• técnicas: immunofluorescence: 1:100-1:1,000; immunohistochemistry: 1:100-1:1,000; western blot: 1:500-1:3,000

Propiedades

• origen biológico: mouse
• Nivel de calidad: 100
• conjugado: unconjugated
• forma del anticuerpo: affinity isolated antibody
• tipo de anticuerpo: primary antibodies
• clon: GT3611, monoclonal
• Formulario: buffered aqueous solution
• mol peso: 242kDa
• reactividad de especies: human, mouse
• concentración: 2.61mg/mL
• técnicas: immunofluorescence: 1:100-1:1,000; immunohistochemistry: 1:100-1:1,000; western blot: 1:500-1:3,000
• isotipo: IgG2b
• Nº de acceso UniProt: O14497
• Condiciones de envío: wet ice
• temp. de almacenamiento: −20°C
• Información sobre el gen: human ... ARID1A(8289)

Descripción

Inmunógeno

Recombinant protein encompassing a sequence within the C-terminus region of human ARID1A.

Aplicación

Suggested starting dilutions are as follows: WB: 1:500-1:3000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.

Acciones bioquímicas o fisiológicas

This gene encodes a member of the SWI/SNF family, whose members have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. It possesses at least two conserved domains that could be important for its function. First, it has a DNA-binding domain that can specifically bind an AT-rich DNA sequence known to be recognized by a SNF/SWI complex at the beta-globin locus. Second, the C-terminus of the protein can stimulate glucocorticoid receptor-dependent transcriptional activation. It is thought that the protein encoded by this gene confers specificity to the SNF/SWI complex and may recruit the complex to its targets through either protein-DNA or protein-protein interactions. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Características y beneficios

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Otras notas

Purification: Affinity purified by Protein G

Forma física

Phosphate-buffered saline, no preservative added.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids
• Clase de riesgo para el agua (WGK): WGK 1
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable