SAB2702179

Anti-ERCC3 antibody produced in rabbit

• Sinónimos: GTF2H, RAD25, TFIIH, XPB
• Código UNSPSC: 12352203
• NACRES: NA.41

Propiedades

• origen biológico: rabbit
• Nivel de calidad: 100
• conjugado: unconjugated
• forma del anticuerpo: purified immunoglobulin
• tipo de anticuerpo: primary antibodies
• clon: polyclonal
• Formulario: liquid
• reactividad de especies: human
• concentración: 1 mg/mL
• técnicas: immunocytochemistry: suitable; immunofluorescence: suitable; western blot: 1:500
• Nº de acceso UniProt: P19447
• Condiciones de envío: wet ice
• temp. de almacenamiento: −20°C
• Información sobre el gen: human ... ERCC3(2071)

Descripción

Inmunógeno

Peptide corresponding to the carboxy-terminus of human XPB.

Aplicación

For WB: Use at a dilution of 1:500 and incubate at RT for 40 minutes. Blocking solution: 3% Milk/TBST at RT for one hour. Optimal dilutions/concentrations should be determined by the researcher.

Acciones bioquímicas o fisiológicas

The human XPB DNA helicase is a subunit of the DNA repair/basal transcription factor TFIIH, and is involved in early steps of the nucleotide excision repair (NER) pathway. Two distinct clinical phenotypes, xeroderma pigmentosum associated with Cockayne′s syndrome (XP/CS) and trichothiodystrophy (TTD), can be due to mutations in the XPB gene.

Características y beneficios

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Forma física

Phosphate-buffered saline, pH 7.2, containing no preservatives

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable