SAB2502028

Anti-SLC6A4 (C-terminal) antibody produced in goat

affinity isolated antibody, buffered aqueous solution

• Sinónimos: 5-HTT, 5-HTTLPR, 5HTT, HTT, solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
• Código UNSPSC: 12352203
• NACRES: NA.41

Propiedades

• origen biológico: goat
• conjugado: unconjugated
• forma del anticuerpo: affinity isolated antibody
• tipo de anticuerpo: primary antibodies
• clon: polyclonal
• Formulario: buffered aqueous solution
• reactividad de especies: rat, bovine, human, mouse
• técnicas: ELISA: suitable; flow cytometry: suitable; immunofluorescence: suitable
• Nº de acceso UniProt: P31645
• Condiciones de envío: wet ice
• temp. de almacenamiento: −20°C
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: human ... SLC6A4(6532)

Descripción

Descripción general

Solute carrier family 6 member 4 (SLC6A4) is also known as 5-hydroxytryptamine transporter (5-HTT). It is an integral membrane protein, which is mapped to human chromosome 17q11.2. The encoded protein is a member of the SLC6 (solute carrier family 6) gene family and is mainly expressed in brain and blood cells.

Inmunógeno

Peptide with sequence C-KERIIKSITPETPT, from the C-terminal region of the protein sequence according to NP_001036.1

Acciones bioquímicas o fisiológicas

Solute carrier family 6 member 4 (SLC6A4) catalyzes the transport of neurotransmitter serotonin from the synaptic space into presynaptic neurons. It plays a vital role in mood and anxiety regulation. Mutation in the gene may alter the expression of serotonin (5HT) in the synaptic cleft, which ultimately leads to schizophrenia. Allelic variations in the gene increase the risk of susceptibility to autism and rigid-compulsive behaviors.

Características y beneficios

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Forma física

Supplied at 0.5 mg/mL in 20mM Tris (pH 7.3) and 150mM NaCl with 0.02% sodium azide and 0.5% bovine serum albumin.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids
• Clase de riesgo para el agua (WGK): WGK 2
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable