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Key Documents

SAB2501424

Sigma-Aldrich

Anti-IGF1 antibody produced in goat

affinity isolated antibody, buffered aqueous solution

Sinónimos:

Anti-IGF1A, Anti-IGFI, Anti-OTTHUMP00000195084, Insulin-like growth factor 1, Insulin-like growth factor 1 (somatomedin C)

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About This Item

Código UNSPSC:
12352203
NACRES:
NA.41

origen biológico

goat

conjugado

unconjugated

forma del anticuerpo

affinity isolated antibody

tipo de anticuerpo

primary antibodies

clon

polyclonal

formulario

buffered aqueous solution

reactividad de especies

human

técnicas

immunohistochemistry: suitable
indirect ELISA: suitable
western blot: suitable

Nº de acceso UniProt

Condiciones de envío

dry ice

temp. de almacenamiento

−20°C

modificación del objetivo postraduccional

unmodified

Información sobre el gen

human ... IGF1(3479)

Descripción general

Insulin-like growth factor 1 (IGF1) is a single polypeptide chain protein with three disulfide bridges. It is mainly produced by the liver and a wide range of extra-hepatic tissues. IGF1 is seen in normal and neoplastic breasts. The IGF1 gene is 84779 bp long and is made of 6 different exons. IGF-1 gene is located on human chromosome 12q23.2.

Inmunógeno

Peptide with sequence RSVRAQRHTD, from the internal region of the protein sequence according to NP_001104753.1; NP_001104754.1; NP_001104755.1; NP_000609.1

Aplicación

Anti-IGF1 antibody produced in goat has been used in western blotting.

Acciones bioquímicas o fisiológicas

Insulin-like growth factor 1 (IGF1) protein is essential for the development of children and adults. It plays a crucial role in general anabolic processes. IGF1 participates in differentiation and cell proliferation. It plays a key role in osteogenesis, muscle repair, and hypertrophy after trauma. IGF1 is also involved in the generation of axons in nerves and regeneration of a nerve after ischemic insult. It is known to participate in the clinical sequelae of Laron′s dwarfism. IGF1 is required for normal breast development.

Características y beneficios

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Forma física

Supplied at 0.5 mg/mL in 20mM Tris (pH 7.3) and 150mM NaCl with 0.02% sodium azide and 0.5% bovine serum albumin.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Código de clase de almacenamiento

10 - Combustible liquids

Clase de riesgo para el agua (WGK)

WGK 2

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable


Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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M Ouni et al.
The pharmacogenomics journal, 16(1), 102-106 (2015-04-15)
Short children using growth hormone (GH) to accelerate their growth respond to this treatment with a variable efficacy. The causes of this individual variability are multifactorial and could involve epigenetics. Quantifying the impact of epigenetic variation on response to treatments
T L Wise
Genes, brain, and behavior, 16(2), 241-249 (2016-09-20)
Fragile X syndrome (FXS) is an inherited form of intellectual disability that is usually caused by expansion of a polymorphic CGG repeat in the 5' untranslated region of the X-linked FMR1 gene, which leads to hypermethylation and transcriptional silencing. Two

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