SAB2501252

Anti-CLEC4C antibody produced in goat

affinity isolated antibody, buffered aqueous solution

• Sinónimos: Anti-BDCA2, Anti-CD303, Anti-CLECSF11, Anti-CLECSF7, C-type lectin domain family 4, member C
• Código UNSPSC: 12352203
• NACRES: NA.41
• conjugado: unconjugated
• application: ELISA (i); WB
• clon: polyclonal
• reactividad de especies: human
• citations: 3
• técnicas: indirect ELISA: suitable; western blot: suitable

Propiedades

• origen biológico: goat
• Nivel de calidad: 100
• conjugado: unconjugated
• forma del anticuerpo: affinity isolated antibody
• tipo de anticuerpo: primary antibodies
• clon: polyclonal
• Formulario: buffered aqueous solution
• reactividad de especies: human
• técnicas: indirect ELISA: suitable; western blot: suitable
• Nº de acceso UniProt: Q8WTT0
• Condiciones de envío: dry ice
• temp. de almacenamiento: −20°C
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: human ... CLEC4C(170482)

Descripción

Descripción general

C-type lectin domain family 4 member C (CLEC4C) is also known as blood dendritic cell antigen 2. It is expressed on plasmacytoid dendritic cells. CLEC4C is a type II transmembrane protein belonging to the C-type lectin (CTLs) superfamily. The protein consists of an extracellular carbohydrate recognition domain (CRD), a transmembrane region and a short cytoplasmic domain. The gene encoding CLEC4C is localized on human chromosome 12.

Inmunógeno

Peptide with sequence QSWTKSQKNCSV, from the Internal region of the protein sequence according to NP_569708.1; NP_987099.1.

Acciones bioquímicas o fisiológicas

C-type lectin domain family 4 member C (CLEC4C) is involved in intracellular signal transduction through the transmembrane adaptor, FcεRγ. It inhibits the secretion of soluble TNF-related apoptosis-inducing ligand (TRAIL). CLEC4C may have a role in ligand internalization.

Características y beneficios

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Forma física

Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Código de clase de almacenamiento: 12 - Non Combustible Liquids
• Clase de riesgo para el agua (WGK): WGK 2
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable