SAB2500606

Anti-LXR α/LXR β antibody produced in goat

affinity isolated antibody, buffered aqueous solution

• Sinónimos: Anti-NR1H3, Anti-RLD-1
• Código UNSPSC: 12352203
• NACRES: NA.41

Propiedades

• origen biológico: goat
• Nivel de calidad: 100
• conjugado: unconjugated
• forma del anticuerpo: affinity isolated antibody
• tipo de anticuerpo: primary antibodies
• clon: polyclonal
• formulario: buffered aqueous solution
• reactividad de especies: human
• técnicas: indirect ELISA: suitable; western blot: suitable
• Nº de acceso UniProt: P55055
• Condiciones de envío: dry ice
• temp. de almacenamiento: −20°C
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: human ... NR1H3; NR1H2(10062)

Descripción

Descripción general

Liver X receptor α and β (LXR-α/LXR-β) are members of LXRs that belong to the nuclear receptor superfamily. LXR-α is expressed predominantly in macrophages, liver, intestine, kidney, lung and adipose tissue. The protein contains a DNA-binding domain that requires the ligand-binding domain to heterodimerize with a retinoid X receptor partner for its DNA-binding activity. The gene encoding this protein is localized on to human chromosome 11p11.2.

Inmunógeno

Peptide with sequence CRLQDKKLPPLLSEI from the internal region of the protein sequence according to NP_005684; NP_009052.

Acciones bioquímicas o fisiológicas

Liver X receptor α (LXR-α) has an important role in the control of cholesterol homeostasis. LXRs have been found to regulate inflammatory response in macrophages. They are also involved in the regulation of cell proliferation.

Características y beneficios

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Forma física

Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Pictogramas: GHS07
• Palabra de señalización: Warning
• Frases de peligro: H315,H319
• Consejos de prudencia: P305 + P351 + P338
• Clasificaciones de peligro: Eye Irrit. 2 - Skin Irrit. 2
• Código de clase de almacenamiento: 10 - Combustible liquids
• Clase de riesgo para el agua (WGK): WGK 2
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable