SAB2500586

Anti-LAT1 antibody produced in goat

affinity isolated antibody, buffered aqueous solution

• Código UNSPSC: 12352203
• NACRES: NA.41

Propiedades

• origen biológico: goat
• conjugado: unconjugated
• forma del anticuerpo: affinity isolated antibody
• tipo de anticuerpo: primary antibodies
• clon: polyclonal
• formulario: buffered aqueous solution
• reactividad de especies: human
• técnicas: indirect ELISA: suitable; western blot: suitable
• Nº de acceso UniProt: O43561
• Condiciones de envío: dry ice
• temp. de almacenamiento: −20°C
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: human ... LAT(27040)

Descripción

Descripción general

Linker for activation of T1 (LAT1) is a tyrosine-phosphorylated integral membrane protein. It is encoded by the gene mapped to human chromosome 16p11.2. LAT is found in peripheral blood lymphocytes, spleen, and thymus. In addition, its expression is also observed in various blood cell types including platelets, megakaryocytes, mast cells, and natural killer cells.

Inmunógeno

Peptide with sequence C-GAPDYENLQELN from the C Terminus of the protein sequence according to NP_055202.1; NP_001014987.1; NP_001014989.1; NP_001014988.1.

Acciones bioquímicas o fisiológicas

Linker for activation of T1 (LAT1) protein is a transmembrane adaptor signaling molecule. It aids in connecting T cell antigen receptor complex (TCR) to intracellular signaling cascades, which is essential for T-cell development and function. Mutation in the LAT1 gene causes severe combined immunodeficiency (SCID).

Características y beneficios

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Forma física

Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids
• Clase de riesgo para el agua (WGK): WGK 2
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable