SAB1306537

ANTI-BECLIN1-BH3 DOMAIN antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

• Sinónimos: BECN1, Beclin-1, Coiled-coil myosin-like BCL2-interacting protein, GT197, Protein GT197
• Código UNSPSC: 12352203
• NACRES: NA.41

Propiedades

• origen biológico: rabbit
• Nivel de calidad: 100
• forma del anticuerpo: affinity isolated antibody
• tipo de anticuerpo: primary antibodies
• clon: polyclonal
• formulario: buffered aqueous solution
• mol peso: 51896 Da
• reactividad de especies: human, mouse
• técnicas: flow cytometry: 1:10-1:50; immunohistochemistry: 1:50-1:100; western blot: 1:1000
• Nº de acceso NCBI: NP_003757.1
• Nº de acceso UniProt: Q14457
• Condiciones de envío: wet ice
• temp. de almacenamiento: −20°C
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: human ... BECN1(8678)

Descripción

Descripción general

Beclin 1 (BECN1) is a tumor suppressor gene. It is a 450 amino-acid protein having three domains. The gene encoding BECN1 is localized on human chromosome 17q21.

Aplicación

ANTI-BECLIN1-BH3 DOMAIN antibody produced in rabbit has been used in Western blotting.

Acciones bioquímicas o fisiológicas

Beclin 1 (BECN1) acts as an initiator of autophagy and is vital in the early stages of autophagosome formation. It has a role in various tumors and cancers. BECN1 is a component of the phosphatidylinositol-3-kinase (PI3K) complex which mediates vesicle-trafficking.

Forma física

Supplied in PBS with 0.09% (W/V) sodium azide

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable