SAB1302339

ANTI-MOUSE MLKL (C-TERM) antibody produced in rabbit

IgG fraction of antiserum, buffered aqueous solution

• Sinónimos: Mixed lineage kinase domain-like protein, Mlkl
• Código UNSPSC: 12352203
• NACRES: NA.41
• conjugado: unconjugated
• application: WB
• clon: polyclonal
• reactividad de especies: mouse
• citations: 21
• técnicas: western blot: 1:250-1:500

Propiedades

• origen biológico: rabbit
• Nivel de calidad: 100
• conjugado: unconjugated
• forma del anticuerpo: IgG fraction of antiserum
• tipo de anticuerpo: primary antibodies
• clon: polyclonal
• Formulario: buffered aqueous solution
• mol peso: 54317 Da
• reactividad de especies: mouse
• técnicas: western blot: 1:250-1:500
• Nº de acceso NCBI: NP_083281.1
• Nº de acceso UniProt: Q9D2Y4
• Condiciones de envío: wet ice
• temp. de almacenamiento: −20°C
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: mouse ... Mlkl(74568)

Descripción

Descripción general

The gene mixed lineage kinase domain-like protein (MLKL) is mapped to human chromosome 16q23. Activated MLKL is localized on the cell membrane.

Aplicación

Anti mouse MLKL (C-TERM) antibody produced in rabbit has been used in immunoblotting.

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Western Blotting (1 paper)

Acciones bioquímicas o fisiológicas

Mixed lineage kinase domain-like protein (MLKL) primarily causes receptor-interacting protein (RIP) kinase–dependent necroptosis. However, during hepatitis, it results in programmed hepatocellular necrosis which is independent of RIPK3. MLKL also participates in endosomal trafficking and in the formation of extracellular vesicles.

Forma física

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids
• Clase de riesgo para el agua (WGK): nwg
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable