SAB1300688

Anti-LIN28A (N-term) antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

• Sinónimos: Anti-CSDD1, Anti-LIN28, Anti-LIN28A, Anti-Lin-28 homolog A, Anti-Zinc finger CCHC domain-containing protein 1
• Código UNSPSC: 12352203
• NACRES: NA.43

Propiedades

• origen biológico: rabbit
• Nivel de calidad: 200
• conjugado: unconjugated
• forma del anticuerpo: affinity isolated antibody
• tipo de anticuerpo: primary antibodies
• clon: polyclonal
• formulario: buffered aqueous solution
• reactividad de especies: human
• técnicas: immunohistochemistry: 1:50-1:100; indirect ELISA: 1:1000
• Nº de acceso NCBI: NP_078950
• Nº de acceso UniProt: Q9H9Z2
• Condiciones de envío: dry ice
• temp. de almacenamiento: −20°C
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: human ... LIN28A(79727)

Descripción

Descripción general

LIN28A acts as a ′translational enhancer′, driving specific mRNAs to polysomes and thus increasing the efficiency of protein synthesis. Its association with the translational machinery and target mRNAs results in an increased number of initiation events per molecule of mRNA and, indirectly, in stabilizing the mRNAs. Binds IGF2 mRNA, MYOD1 mRNA, ARBP/36B4 ribosomal protein mRNA and its own mRNA. It is essential for skeletal muscle differentiation through the translational up-regulation of IGF2 expression.

Inmunógeno

LIN28A (NP_078950, 15-49)
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human LIN28A.

Forma física

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids
• Clase de riesgo para el agua (WGK): nwg
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable