S5439

Src human

≥80% (SDS-PAGE), recombinant, expressed in baculovirus infected insect cells, buffered aqueous glycerol solution, histidine-tagged

• Número MDL: MFCD03458574
• Código UNSPSC: 12352200
• NACRES: NA.32

Propiedades

• recombinante: expressed in baculovirus infected insect cells
• Ensayo: ≥80% (SDS-PAGE)
• Formulario: buffered aqueous glycerol solution
• mol peso: 60 kDa
• concentración: ~0.58 mg/mL protein (Bradford assay)
• Nº de acceso UniProt: P12931
• aplicaciones: cell analysis
• Condiciones de envío: dry ice
• temp. de almacenamiento: −70°C
• Información sobre el gen: human ... SRC(6714)

Descripción

Descripción general

SRC proto-oncogene, non-receptor tyrosine kinase (SRC) belongs to the family of non-receptor tyrosine kinases. It contains an amino-terminal domain, conserved Src-homology domains (SH2 and SH3), a tyrosine kinase domain and the carboxyl-terminus. The gene encoding this protein is localized on human chromosome 20q11.23.

Aplicación

Human Src has been used to study the kinetics of Src entrapped in a series of different sol-gel derived materials.

Acciones bioquímicas o fisiológicas

SRC proto-oncogene, non-receptor tyrosine kinase (SRC) phosphorylates membrane proteins and nucleoproteins and activates various intracellular signaling cascades. It has been associated with a number of human malignancies and cancers.

Definición de unidad

One unit will phosphorylate one nmole of poly(Gly:Tyr) 4:1 per minute at pH 7.5 at 30°C.

Forma física

Solution in 50 mM Tris pH 7.5, 0.05 mM EDTA, 1 mM DTT, 100 mM NaCl, 0.05% NP-40, and 50% glycerol.

Información de seguridad

• Código de clase de almacenamiento: 12 - Non Combustible Liquids
• Clase de riesgo para el agua (WGK): WGK 1
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable