S4441
D,L-Sulforaphane
≥90% (HPLC), liquid, phase II detoxification enzymes inducer
Sinónimos:
1-Isothiocyanato-4-(methylsulfinyl)-butane
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About This Item
Fórmula empírica (notación de Hill):
C6H11NOS2
Número de CAS:
Peso molecular:
177.29
Número MDL:
Código UNSPSC:
12352200
ID de la sustancia en PubChem:
NACRES:
NA.77
Productos recomendados
Nombre del producto
DL-Sulforaphane, ≥90% (HPLC), synthetic, liquid
origen biológico
synthetic
Nivel de calidad
Ensayo
≥90% (HPLC)
Formulario
liquid
solubilidad
DMSO: soluble 40 mg/mL
H2O: insoluble
compatibilidad
for use with ABI 7500
Condiciones de envío
dry ice
temp. de almacenamiento
−20°C
cadena SMILES
CS(=O)CCCCN=C=S
InChI
1S/C6H11NOS2/c1-10(8)5-3-2-4-7-6-9/h2-5H2,1H3
Clave InChI
SUVMJBTUFCVSAD-UHFFFAOYSA-N
Aplicación
LNCaP prostate cancer cells were treated with DL-Sulforaphane to study the effect on androgen receptor. Effects on malathion toxicity was studied in rats by treating them with DL-Sulforaphane.
Acciones bioquímicas o fisiológicas
Selective inducer of phase II detoxification enzymes with anticarcinogenic properties. Organosulfur compound found in cruciferous vegetables, including broccoli.
Sulforaphane is an anti-cancer, anti-microbial and anti-diabetic compound found in cruciferous vegetables. It induces the production of detoxifying enzymes such as quinone reductase and glutathione S-transferase that cause xenobiotic transformation. Sulforaphane also increases the transcription of tumor suppressor proteins and inhibits histone deacetylases. It modulates inflammatory responses by suppressing the LPS-mediated expression of iNOS, COX-2, IL-1β and TNF-α.
Código de clase de almacenamiento
10 - Combustible liquids
Clase de riesgo para el agua (WGK)
WGK 3
Equipo de protección personal
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
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