S0577

Streptokinase C from Streptococcus sp.

lyophilized solid, ≥3,500 unit/mg solid

• Sinónimos: Streptokinase
• Comisión internacional de enzimas: 3.4.99.0 (BRENDA, IUBMB)
• Código UNSPSC: 12352204
• NACRES: NA.54

Propiedades

• origen biológico: bacterial (Streptococcus sp.)
• Nivel de calidad: 200
• recombinante: expressed in E. coli
• Ensayo: 40—60% protein (biuret)
• Formulario: lyophilized solid
• actividad específica: ≥3,500 unit/mg solid
• color: off-white to light yellow
• aplicaciones: life science and biopharma
• temp. de almacenamiento: −20°C
• Información sobre el gen: Streptococcus pyogenes ... SKC(134997)

Descripción

Descripción general

Research area: Cell Signaling

Streptokinase is an extracellular enzyme, a single-chain polypeptide produced by several strains of β-hemolytic Streptococci. It is composed of multiple structural domains like α-, β-, and γ-domains that are involved in various functions.

Aplicación

Streptokinase C from Streptococcus sp. has been used to quantitate the survival of Staphylococcus aureus in whole human blood.

Acciones bioquímicas o fisiológicas

Streptokinase shows fibrinolytic activity by triggering the circulatory plasminogen either via a fibrin-dependent or fibrin-independent mechanism. Streptokinase has been studied majorly in terms of its therapeutic efficacy and treating myocardial infarction to dissolve clots.

Definición de unidad

One unit will liquify a standard clot of fibrinogen, plasminogen, and thrombin at pH 7.5 at 37 °C in 10 min.

Forma física

Lyophilized powder containing approx. 50% bovine serum albumin (total protein by biuret) with sodium glutamate.

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable