Saltar al contenido
Merck

RAB0802

Sigma-Aldrich

Mouse IgG1 ELISA Kit

Sinónimos:

IgG1, Immunoglobulin G1

Iniciar sesiónpara Ver la Fijación de precios por contrato y de la organización


About This Item

Código UNSPSC:
41116158
NACRES:
NA.32

reactividad de especies

mouse

técnicas

ELISA: suitable

assay range

inter-assay cv: <10%
intra-assay cv: <12%

Condiciones de envío

wet ice

temp. de almacenamiento

−20°C

Descripción general

Immunoglobulin G (IgG) is the most prevalent protein found in the human serum. About 10–20% of plasma protein accounts for IgG. IgG1 is the major Ig isotype in murine serum. It resembles human IgG4 functionally. Murine immunoglobulin G1 (IgG1) is capable of blocking the complex formation of IgG2a, IgG2b, and IgG3 with C1q. C1q-mediated complement activation by IgG2a can be blocked by murine IgG1. Because of their likely inhibitory influence on both complement and classical Fcγ receptor (FcγR) activation, murine IgG1 may have the greatest inhibitory capacity toward all other IgG types. The antibody pair provided in this kit recognizes mouse IgG1.

Aplicación

For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)

Los componentes del kit también están disponibles por separado

Referencia del producto
Descripción
SDS

  • RABTMB3ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)SDS

  • RABSTOP3ELISA Stop Solution (Item I)SDS

  • RABWASH420X Wash Buffer (Item B)SDS

Pictogramas

Corrosion

Palabra de señalización

Warning

Frases de peligro

Consejos de prudencia

Clasificaciones de peligro

Met. Corr. 1

Código de clase de almacenamiento

8A - Combustible corrosive hazardous materials

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable


Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

¿Ya tiene este producto?

Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.

Visite la Librería de documentos

Gina-Maria Lilienthal et al.
Frontiers in immunology, 9, 958-958 (2018-06-06)
IgG antibodies (Abs) mediate their effector functions through the interaction with Fcγ receptors (FcγRs) and the complement factors. The main IgG-mediated complement activation pathway is induced through the binding of complement C1q to IgG Abs. This interaction is dependent on
Roxanne Collin et al.
Journal of immunology (Baltimore, Md. : 1950), 193(7), 3503-3512 (2014-08-29)
Autoimmune diseases result from a break in immune tolerance. Various mechanisms of peripheral tolerance can protect against autoimmunity, including immunoregulatory CD4(-)CD8(-) double-negative (DN) T cells. Indeed, we have previously shown that diabetes-prone mouse strains exhibit a low proportion of DN
Arjan van der Flier et al.
PloS one, 10(4), e0124930-e0124930 (2015-04-24)
We recently developed a longer lasting recombinant factor VIII-Fc fusion protein, rFVIIIFc, to extend the half-life of replacement FVIII for the treatment of people with hemophilia A. In order to elucidate the biological mechanism for the elongated half-life of rFVIIIFc
Chanjuan Shen et al.
Vaccine, 32(41), 5337-5342 (2014-08-06)
A better understanding of immune responses in human infants could lead to more effective immunization and vaccination strategies in early life. Since antibodies are key components of protective vaccine responses, we examined developmental changes in serum levels of immunoglobulins (IgG
J M Birmingham et al.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 44(9), 1188-1199 (2014-07-22)
Although morbidity and mortality rates from asthma are highest in patients > 65 years of age, the effect of older age on airway inflammation in asthma is not well established. To investigate age-related differences in the promotion of allergic inflammation

Nuestro equipo de científicos tiene experiencia en todas las áreas de investigación: Ciencias de la vida, Ciencia de los materiales, Síntesis química, Cromatografía, Analítica y muchas otras.

Póngase en contacto con el Servicio técnico