RAB0780

Mouse Tyro3 / Tyrosine-protein Kinase Receptor TYRO3 ELISA Kit

• Código UNSPSC: 41116158
• NACRES: NA.32

Propiedades

• reactividad de especies: mouse
• envase: kit of 96 wells (12 strips x 8 wells)
• técnicas: ELISA: suitable
• entrada: sample type cell culture supernatant(s); sample type serum; sample type plasma
• assay range: inter-assay cv: <12%; intra-assay cv: <10%; sensitivity: 0.4 ng/mL; standard curve range: 0.416-100 ng/mL
• método de detección: colorimetric
• Condiciones de envío: wet ice
• temp. de almacenamiento: −20°C
• Información sobre el gen: mouse ... Tyro3(22174)

Descripción

Descripción general

The antibody pair provided in this kit recognizes mouse Tyro3.

Aplicación

For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)

Acciones bioquímicas o fisiológicas

Tyrosine-protein kinase receptor (TYRO3) is a transmembrane tyrosine kinase receptor. It plays a significant role in the brain development during embryogenesis. It plays an important role in apoptotic cell clearance. In hepatocellular carcinoma, it is associated with tumor growth, aggressiveness and liver dysfunction. Mutations in the TYRO3 gene intronic regions are linked with asthma. TYRO3 is also a suppressor of type 2 immunity. As part of the TAM (TYRO3, AXL and MER receptors) family, it is activated by PROS1 (protein S) and GAS6 (growth arrest-specific gene 6). Changes in the expression of TYRO3 are linked with the proliferation and survival of cancer cells. Absence of TYRO3 in mice results in neurological disorders.

Los componentes del kit también están disponibles por separado

• RABTMB3 ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)
• RABSTOP3 ELISA Stop Solution (Item I)
• RABWASH4 20X Wash Buffer (Item B)

Información de seguridad

• Pictogramas: GHS05
• Palabra de señalización: Warning
• Frases de peligro: H290
• Consejos de prudencia: P234 - P390
• Clasificaciones de peligro: Met. Corr. 1
• Código de clase de almacenamiento: 8A - Combustible corrosive hazardous materials
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable