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RAB0537

Sigma-Aldrich

Human FABP2 / Fatty Acid-Binding Protein, Intestinal ELISA Kit

for serum, plasma, cell culture supernatants and urine

Sinónimos:

FABP2 ELISA Kit, Intestinal FABP2 Detection

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About This Item

Código UNSPSC:
41116158
NACRES:
NA.32

reactividad de especies

human

envase

kit of 96 wells (12 strips x 8 wells)

técnicas

ELISA: suitable

entrada

sample type plasma
sample type serum
sample type urine
sample type cell culture supernatant(s)

assay range

inter-assay cv: <10%
intra-assay cv: <12%
sensitivity: 25 pg/mL

método de detección

colorimetric

Condiciones de envío

wet ice

temp. de almacenamiento

−20°C

Información sobre el gen

human ... FABP2(2169)

Descripción general

The antibody pair provided in this kit detects Intestinal, Human Fatty Acid-Binding Protein in serum, plasma, cell culture supernatants, and urine.

Fatty acid-binding protein (FABP2) is an intracellular protein, encoded by the gene mapped to human chromosome 4q28–q31.It is expressed in intestinal enterocytes. FABP2 codes for intestinal FABP (I-FABP).

Aplicación

For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)

Acciones bioquímicas o fisiológicas

Fatty acid-binding protein (FABP2) plays a vital role in the absorption and intracellular migration of dietary long-chain fatty acids. It also helps in the metabolism of fatty acids. FABP2 acts as a candidate gene for diabetes and insulin resistance. It is also implicated in lipid metabolism and adipogenesis.

Otras notas

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.

Los componentes del kit también están disponibles por separado

Referencia del producto
Descripción
SDS
  • RABTMB3ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)SDS
  • RABSTOP3ELISA Stop Solution (Item I)SDS
  • RABELADBELISA 5X Assay/Sample Diluent Buffer B (Item E1)SDS
  • RABELADCELISA 1X Assay/Sample Diluent Buffer C (Item L)SDS
  • RABWASH420X Wash Buffer (Item B)SDS

Pictogramas

Corrosion
GHS05

Palabra de señalización

Warning

Frases de peligro

H290

Consejos de prudencia

P234 - P390

Clasificaciones de peligro

Met. Corr. 1

Código de clase de almacenamiento

8A - Combustible corrosive hazardous materials

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Fatty acid-binding proteins: role in metabolic diseases and potential as drug targets.
Furuhashi M and Gokhan S H
Nature Reviews. Drug Discovery, 7(6), 489-489 (2008)
Nicole U Stoffel et al.
The Lancet. Haematology, 4(11), e524-e533 (2017-10-17)
Current guidelines to treat iron deficiency recommend daily provision of ferrous iron divided through the day to increase absorption. However, daily dosing and split dosing might increase serum hepcidin and decrease iron absorption from subsequent doses. Our study aim was
Brynjulf Mortensen et al.
Gastroenterology, 157(3), 637-646 (2019-05-17)
Enteropathy and small-intestinal ulcers are common adverse effects of nonsteroidal anti-inflammatory drugs such as acetylsalicylic acid (ASA). Safe, cytoprotective strategies are needed to reduce this risk. Specific bifidobacteria might have cytoprotective activities, but little is known about these effects in
Bret McCarty et al.
Frontiers in immunology, 9, 1901-1901 (2018-09-11)
T follicular helper (Tfh) cells are crucial for B cell differentiation and antigen-specific antibody production. Dysregulation of Tfh-mediated B cell help weakens B cell responses in HIV infection. Moreover, Tfh cells in the lymph node and peripheral blood comprise a
Stefan P Kastl et al.
Shock (Augusta, Ga.), 51(4), 410-415 (2018-05-31)
Acute heart failure and cardiogenic shock are associated with an impaired intestinal perfusion, which may lead to a release of cytoplasmatic proteins by hypoxic epithelial injury. Intestinal fatty acid binding protein (iFABP), highly specific for the small bowel enterocyte, may
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