RAB0036
Human Carbonic Anhydrase IX ELISA Kit
for serum, plasma, cell culture supernatant and urine
Sinónimos:
CA9
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About This Item
Código UNSPSC:
41116158
NACRES:
NA.32
Productos recomendados
reactividad de especies
human
envase
kit of 96 wells (12 strips x 8 wells)
técnicas
ELISA: suitable
capture ELISA: suitable
entrada
sample type plasma
sample type serum
sample type cell culture supernatant(s)
sample type urine
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 0.2 pg/mL
standard curve range: 0.205-50 pg/mL
método de detección
colorimetric
Condiciones de envío
wet ice
temp. de almacenamiento
−20°C
Información sobre el gen
human ... CA9(768)
Descripción general
Carbonic anhydrase IX (CA9) belongs to the zinc-containing metalloenzymes family. The protein is encoded by the gene mapped to human chromosome 9p. The encoded protein is localized on cell membrane and is characterized with an N-terminal proteoglycan-like domain (PG), a CA catalytic domain (CA), a transmembrane helical segment and a short intra-cytoplasmic tail. CA9 is expressed at very low levels in normal tissues (mostly in gastrointestinal tract), but it is expressed at high level in various cancer tissues, such as renal, lung, cervical, ovarian, esophageal and breast cancer.
The Human CA-IX (Carbonic Anhydrase IX) ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human CA-IX in serum, plasma, cell culture supernatants and urine.
Inmunógeno
Recombinant Human CA9
Aplicación
For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Acciones bioquímicas o fisiológicas
Carbonic anhydrase IX (CA9) aids in reversible hydration of carbon dioxide to carbonic acid and bicarbonate. CA9 functions as a promising biomarker for diagnosing clear cell renal cell carcinoma (ccRCC), tumor hypoxia and prostate cancer (PC). In addition to pH control, CA9 also plays a vital role in cell proliferation, adhesion and tumor invasion.
Otras notas
A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.
Please type the word sample in the text box provided for lot number.
Los componentes del kit también están disponibles por separado
Referencia del producto
Descripción
SDS
Palabra de señalización
Warning
Frases de peligro
Consejos de prudencia
Clasificaciones de peligro
Met. Corr. 1
Código de clase de almacenamiento
8A - Combustible corrosive hazardous materials
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