PZ0159

MCOPPB trihydrochloride hydrate

>98% (HPLC)

• Sinónimos: 1-[1-(1-Methylcyclooctyl)-4-piperidinyl]-2-[(3R)-3-piperidinyl]-1H-benzimidazole trihydrochloride hydrate
• Fórmula empírica (notación de Hill): C₂₆H₄₀N₄ · 3 HCl · xH₂O
• Número de CAS: 1028969-49-4
• Peso molecular: 518.01 (anhydrous basis)
• Código UNSPSC: 51111800
• ID de la sustancia en PubChem: 329823741
• NACRES: NA.77

Propiedades

• Nivel de calidad: 100
• Análisis: >98% (HPLC)
• formulario: powder
• condiciones de almacenamiento: desiccated
• color: white to tan
• solubilidad: H₂O: ≥13 mg/mL
• temp. de almacenamiento: room temp
• cadena SMILES: O.Cl.Cl.Cl.CC1(CCCCCCC1)N2CCC(CC2)n3c(nc4ccccc34)[C@@H]5CCCNC5
• InChI: 1S/C26H40N4.3ClH.H2O/c1-26(15-7-3-2-4-8-16-26)29-18-13-22(14-19-29)30-24-12-6-5-11-23(24)28-25(30)21-10-9-17-27-20-21;;;;/h5-6,11-12,21-22,27H,2-4,7-10,13-20H2,1H3;3*1H;1H2
• Clave InChI: UQBVSGBDJOJHIP-UHFFFAOYSA-N

Descripción

Acciones bioquímicas o fisiológicas

MCOPPB trihydrochloride is a potent non-peptide nociceptin/orphanin FQ peptide (NOP)-receptor full agonist [or opioid-receptor-like-1 (ORL1) receptor agonist]. MCOPPB is the most potent novel non-peptide NOP full agonist in vitro and an orally potent anxiolytic in the mice. It inhibited signaling through the NOP receptor in the mouse brain, suggesting that it penetrated into the brain after it was orally administered. It did not affect locomotor activity or memory, nor did it contribute to ethanol-induced hypnosis.

Características y beneficios

This compound is featured on the Opioid Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable