P7123

Protein Kinase Cν (PKCν) Active human

recombinant, expressed in E. coli, ≥75% (SDS-PAGE), buffered aqueous glycerol solution

• Sinónimos: PKD3, Protein Kinase C nu
• Número MDL: MFCD07371119
• Código UNSPSC: 12352202
• NACRES: NA.32

Propiedades

• recombinante: expressed in E. coli
• Nivel de calidad: 200
• Ensayo: ≥75% (SDS-PAGE)
• Formulario: buffered aqueous glycerol solution
• mol peso: protein apparent mol wt ~142 kDa
• Nº de acceso UniProt: O94806
• Condiciones de envío: dry ice
• temp. de almacenamiento: −70°C
• Información sobre el gen: human ... PRKD3(23683)

Descripción

Aplicación

Kinase activity is measured as the molar amount of phosphate incorporated into the CREBtide substrate peptide (KRREILSRRPSYR) per minute per mg protein at 30 °C using a final concentration of 50 μM [³²P] ATP.

Acciones bioquímicas o fisiológicas

PKCν, also known as PKD3, is a member of the protein kinase C (PKC) family of serine/threonine kinases that play critical roles in the regulation of cellular differentiation and proliferation in many cell types. PKCν is an important physiologic target of the B-cell receptor (BCR) and exhibits activation upon BCR engagement.

Forma física

Solution of 5 μg in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 0.25 mM DTT, 0.1 mM EGTA, and 30% glycerol

Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids