N0258

N-Nitrosodiethylamine

ISOPAC^®

• Sinónimos: Diethylnitrosamine
• Fórmula lineal: (C₂H₅)₂NNO
• Número de CAS: 55-18-5
• Peso molecular: 102.14
• Beilstein: 1744991
• Número CE: 200-226-1
• Número MDL: MFCD00013890
• Código UNSPSC: 12352116
• ID de la sustancia en PubChem: 24897417
• NACRES: NA.25

Propiedades

• Nivel de calidad: 100
• Formulario: liquid
• bp: 177 °C (lit.)
• densidad: 0.95 g/mL (lit.)
• cadena SMILES: CCN(CC)N=O
• InChI: 1S/C4H10N2O/c1-3-6(4-2)5-7/h3-4H2,1-2H3
• Clave InChI: WBNQDOYYEUMPFS-UHFFFAOYSA-N

Descripción

Aplicación

N-Nitrosodiethylamine (NDEA) has been used as a hepatocarcinogen/DNA damaging agent. It has been used as a calibration standard for gas–liquid chromatography.

Acciones bioquímicas o fisiológicas

N-Nitrosodiethylamine (NDEA) is a potent hepatocarcinogenic dialkylnitrosoamine. It is mainly present in tobacco smoke, water, cheddar cheese, cured, fried meals and many alcoholic beverages. NDEA is responsible for the changes in the nuclear enzymes associated with DNA repair/replication. It results in various tumors in all animal species. The main target organs are the nasal cavity, trachea, lung, esophagus and liver.

Envase

Packaged in a 100 mL serum bottle with silicon/PTFE septum and aluminum tear seal.

Precaución

Injecting any compatible solvent permits preparation of any desired strength solution without exposure.

Reconstitución

Dissolving the contents in 100 mL of solvent yields a 1% solution.

Información legal

Isopac is a registered trademark of Merck KGaA, Darmstadt, Germany

Información de seguridad

• Pictogramas: GHS06,GHS08
• Palabra de señalización: Danger
• Frases de peligro: H301,H350,H412
• Consejos de prudencia: P202 - P264 - P270 - P273 - P280 - P301 + P310
• Clasificaciones de peligro: Acute Tox. 3 Oral - Aquatic Chronic 3 - Carc. 1B
• Código de clase de almacenamiento: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Clase de riesgo para el agua (WGK): WGK 3
• Equipo de protección personal: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter