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Merck

MAK164

Sigma-Aldrich

Intracellular Hydrogen Peroxide Assay

sufficient for 200 fluorometric tests (green fluorescence)

Sinónimos:

Hydrogen Peroxide Detection in Cells

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About This Item

Número CE:
Código UNSPSC:
12161503
NACRES:
NA.84

uso

sufficient for 200 fluorometric tests (green fluorescence)

método de detección

fluorometric

enfermedades relevantes

aging/geriatric diseases; neurological disorders; pulmonary disorders; orthopedic diseases; cardiovascular diseases

temp. de almacenamiento

−20°C

Descripción general

Hydrogen peroxide, a reactive oxygen species produced through the metabolism of molecular oxygen, serves as both an intracellular signaling messenger and a source of oxidative stress. Hydrogen peroxide is generated in cells via multiple mechanisms such as the NOX-mediated ROS production by neutrophils and macrophages (respiratory burst) or by the dismutase of superoxide anions produced as a result of electron leak during mitochondrial respiration. Abnormal hydrogen peroxide production contributes to oxidative cell damage and the progression of diseases such as asthma, atherosclerosis, osteoporosis, and neurodegeneration.

Aplicación

Intracellular hydrogen peroxide assay kit has been used to measure intracellular hydrogen peroxide levels.

Características y beneficios

Compatible with high-throughput handling systems.

Idoneidad

This kit is suitable for the detection of hydrogen peroxide in living cells and a variety of samples such as cell extracts and liquids.

Principio

The Intracellular Hydrogen Peroxide Assay Kit provides a simple and reproducible method to quantify hydrogen peroxide levels in living cells and in a variety of other samples such as cellular extracts. This kit utilizes a unique cell-permeable sensor that generates a fluorescent product (λex = 490/λem = 520 nm) after reaction with hydrogen peroxide that can be analyzed by a fluorescent microplate reader, flow cytometer, or fluorescent microscope.

Código de clase de almacenamiento

10 - Combustible liquids

Clase de riesgo para el agua (WGK)

WGK 3


Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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