MAK156
Fatty Acid Uptake Kit
sufficient for 100 fluorometric tests
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About This Item
Productos recomendados
uso
sufficient for 100 fluorometric tests
método de detección
fluorometric
enfermedades relevantes
endocrinological disorders, diabetes; gastrointestinal diseases; cancer
temp. de almacenamiento
−20°C
Categorías relacionadas
Descripción general
Fatty acids are critical for many biological processes including energy metabolism and the synthesis of structural cellular components. The facilitated uptake of fatty acids, presumably through fatty acid transport proteins, is thought to be regulated at multiple levels. The dysregulation of fatty acid uptake may contribute to diseases such as obesity, type 2 diabetes, and hepatic steatosis.
Idoneidad
This kit is suitable for the measurement of fatty acid uptake in cells containing fatty acid transporters
Principio
This kit is provides a simple and sensitive method for the measurement of fatty acid uptake in cells containing fatty acid transporters. This kit uses a proprietary dodecanoic acid fluorescent fatty acid substrate whose uptake into cells result in an increase in fluorescence intensity (λex = 485/λem = 515 nm).
Código de clase de almacenamiento
10 - Combustible liquids
Certificados de análisis (COA)
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Triphenyl phosphate (TPhP) is an environmental PPARγ ligand, and growing evidence suggests that it is a metabolic disruptor. We have shown previously that the structurally similar ligand, tributyltin, does not induce brite adipocyte gene expression. Here, using in vivo and
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