M7397

L-(−)-Malic acid

suitable for cell culture, BioReagent, suitable for insect cell culture

• Sinónimos: (S)-(−)-2-Hydroxysuccinic acid, L-Hydroxybutanedioic acid
• Fórmula lineal: HO₂CCH₂CH(OH)CO₂H
• Número de CAS: 97-67-6
• Peso molecular: 134.09
• Beilstein: 1723541
• Número CE: 202-601-5
• Número MDL: MFCD00064213
• Código UNSPSC: 12352205
• ID de la sustancia en PubChem: 24897161
• NACRES: NA.75

Propiedades

• origen biológico: microbial
• grado: reagent
• Línea del producto: BioReagent
• Ensayo: ≥95% (titration)
• Formulario: powder
• técnicas: cell culture | insect: suitable; cell culture | mammalian: suitable
• mp: 101-103 °C (lit.)
• solubilidad: water: 100 mg/mL, clear to slightly hazy, colorless
• cadena SMILES: O[C@@H](CC(O)=O)C(O)=O
• InChI: 1S/C4H6O5/c5-2(4(8)9)1-3(6)7/h2,5H,1H2,(H,6,7)(H,8,9)/t2-/m0/s1
• Clave InChI: BJEPYKJPYRNKOW-REOHCLBHSA-N

Descripción

Descripción general

Malic acid is used as a component of insect tissue culture. It is also useful as an acidulant in soft drinks, jams, fruit and vegetable juices.

Aplicación

Malic acid has been used:

• to induce basal respiration in mitochondrial cell culture
• to measure the mitochondrial ETC (electron transport chain) activity
• as a component of mitochondrial substrate stock

Acciones bioquímicas o fisiológicas

Malic acid is a part of cellular metabolism. Its application is recognized in pharmaceutics. It is useful in the treatment of hepatic malfunctioning, effective against hyper-ammonemia. It is used as a part of amino acid infusion. Malic acid also serves as a nanomedicine in the treatment of brain neurological disorders. A TCA (Krebs cycle) intermediate and partner in the malic acid aspartate shuttle.

Información de seguridad

• Pictogramas: GHS07
• Palabra de señalización: Warning
• Frases de peligro: H315,H319
• Consejos de prudencia: P264 - P280 - P302 + P352 - P305 + P351 + P338 - P332 + P313 - P337 + P313
• Clasificaciones de peligro: Eye Irrit. 2 - Skin Irrit. 2
• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 1
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable
• Equipo de protección personal: dust mask type N95 (US), Eyeshields, Gloves