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M4434

Sigma-Aldrich

Anti-Mouse IgG2a (heavy chain specific) antibody produced in goat

affinity isolated antibody, lyophilized powder

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About This Item

Número MDL:
MFCD02570704
Código UNSPSC:
12352203
NACRES:
NA.46

origen biológico

goat

conjugado

unconjugated

forma del anticuerpo

affinity isolated antibody

tipo de anticuerpo

secondary antibodies

clon

polyclonal

formulario

lyophilized powder

técnicas

Ouchterlony double diffusion: suitable

temp. de almacenamiento

2-8°C

modificación del objetivo postraduccional

unmodified

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Descripción general

IgG antibody subtype is the most abundant serum immunoglobulins of the immune system. It is secreted by B cells and is found in blood and extracellular fluids and provides protection from infections caused by bacteria, fungi and viruses. Maternal IgG is transferred to fetus through the placenta that is vital for immune defence of the neonate against infections.
Anti-Mouse IgG2a (heavy chain specific) antibody recognizes mouse IgG2a when tested against purified mouse IgA, IgG1, IgG2a, IgG2b, IgG3, and IgM, myeloma proteins.

Inmunógeno

purified mouse IgG2a (myeloma protein).

Aplicación

Anti-Mouse IgG2a (heavy chain specific) antibody is suitable for Ouchterlony double diffusion.
Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Enzyme-linked immunosorbent assay (1 paper)

Forma física

Lyophilized from 0.01 M sodium phosphate, 0.015 M sodium chloride, pH 7.2.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Equipo de protección personal

Eyeshields, Gloves, type N95 (US)

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Anti-Human IgG (Fc specific) antibody produced in goat affinity isolated antibody, buffered aqueous solution

Sigma-Aldrich

I2136

Anti-Human IgG (Fc specific) antibody produced in goat

Hiwa Karimi et al.
Reproductive toxicology (Elmsford, N.Y.), 69, 196-203 (2017-03-13)
A study using a mouse IVF model was conducted to examine the hypothesis that in vitro fertilization (IVF) treatment may lead to immune system alteration in the offspring. Phagocytic activity and lymphocyte proliferative responses to mitogen, alloantigen, and purified protein
Roselind S Lam et al.
Journal of immunology (Baltimore, Md. : 1950), 193(5), 2349-2362 (2014-07-30)
The role of the macrophage in the immunopathology of periodontitis has not been well defined. In this study, we show that intraoral inoculation of mice with Porphyromonas gingivalis resulted in infection, alveolar bone resorption, and a significant increase in F4/80(+)
S Hashira et al.
Pediatrics international : official journal of the Japan Pediatric Society, 42(4), 337-342 (2000-09-15)
Maternal immunoglobulin G (IgG), transferred across the placenta to the fetus during intrauterine life, is an important component of the neonatal immunological defence mechanisms against infection. There is controversy with respect to differences in placental transfer of the different IgG

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