L8000

L-Leucine

≥98% (HPLC), suitable for ligand binding assays

• Sinónimos: (S)-2-Amino-4-methylpentanoic acid
• Fórmula lineal: (CH₃)₂CHCH₂CH(NH₂)CO₂H
• Número de CAS: 61-90-5
• Peso molecular: 131.17
• Beilstein: 1721722
• Número CE: 200-522-0
• Número MDL: MFCD00002617
• Código UNSPSC: 12352209
• eCl@ss: 32160406
• ID de la sustancia en PubChem: 24896488
• NACRES: NA.26

Propiedades

• product name: L-Leucine, reagent grade, ≥98% (HPLC)
• grado: reagent grade
• Análisis: ≥98% (HPLC)
• formulario: powder
• técnicas: ligand binding assay: suitable
• impurezas: isoleucine and methionine, essentially free
• color: white to off-white
• mp: >300 °C (lit.)
• aplicaciones: peptide synthesis
• cadena SMILES: CC(C)C[C@H](N)C(O)=O
• InChI: 1S/C6H13NO2/c1-4(2)3-5(7)6(8)9/h4-5H,3,7H2,1-2H3,(H,8,9)/t5-/m0/s1
• Clave InChI: ROHFNLRQFUQHCH-YFKPBYRVSA-N

Descripción

Aplicación

L-Leucine has been used as an agonist of mechanistic target of rapamycin (mTOR) to determine whether AMPK/mTOR pathway is involved in berberine-mediated autophagy in J774A.1 cells. It has also been used for the selection of transformed cells.

Acciones bioquímicas o fisiológicas

Leucine is a non-glucogenic, essential amino acid. It is a branched-chain amino acid that is a structural component of proteins. Leucine positively influences insulin release to eliminate toxic sugars out of the blood. The degradation of leucine leads to the formation of ketone bodies.

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 1
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable
• Equipo de protección personal: Eyeshields, Gloves, type N95 (US)