I5521

Monoclonal Anti-Interferon-γ antibody produced in mouse

clone 25718, purified immunoglobulin, lyophilized powder

• Sinónimos: Anti-IFN-γ
• Número MDL: MFCD00162308
• Código UNSPSC: 51111800
• NACRES: NA.41

Propiedades

• origen biológico: mouse
• Nivel de calidad: 100
• conjugado: unconjugated
• forma del anticuerpo: purified immunoglobulin
• tipo de anticuerpo: primary antibodies
• clon: 25718, monoclonal
• Formulario: lyophilized powder
• reactividad de especies: human
• técnicas: immunocytochemistry: 8-25 μg/mL using immersion fixed human peripheral blood mononuclear cells stimulated with PMA and ionomycin; neutralization: suitable
• impurezas: endotoxin, tested
• isotipo: IgG2a
• Nº de acceso UniProt: P01579
• temp. de almacenamiento: −20°C
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: human ... IFNG(3458)

Descripción

Inmunógeno

recombinant human interferon-γ, expressed and purified from Escherichia coli.

Acciones bioquímicas o fisiológicas

Interferons (IFNs) are cytokines that are secreted in response to viral or bacterial infections and tumorigenesis. IFN-γ binds to specific receptor complex consisting of IFNγR1 and IFNγR2. There are many pathways that are mediated by IFN-γ binding such as JAK/STAT1, AP-1, NF-κB, STAT3 and STAT5. IFN-γ is pleotropic and performs various functions related to immune response, inflammation, differentiation and activation of T cells, cell cycle and apoptosis.

Forma física

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing 5% trehalose.

Nota de preparación

Purified using protein A affinity chromatography.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 2
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable
• Equipo de protección personal: Eyeshields, Gloves, type N95 (US)