I4765

Human IgG4 Lambda, Recombinant Protein

purified immunoglobulin

• Sinónimos: Human IgG4 Protein
• Código UNSPSC: 12352203
• NACRES: NA.41

Propiedades

• origen biológico: human (recombinant)
• Nivel de calidad: 200
• conjugado: unconjugated
• forma del anticuerpo: purified immunoglobulin
• Condiciones de envío: dry ice
• temp. de almacenamiento: −20°C

Descripción

Descripción general

IgG antibody subtype is the most abundant serum immunoglobulins of the immune system. It is secreted by B cells and is found in blood and extracellular fluids and provides protection from infections caused by bacteria, fungi and viruses. Maternal IgG is transferred to fetus through the placenta that is vital for immune defense of the neonate against infections. IgG4 is the least abundant of the IgG subclass. IgG4-related systemic diseases include autoimmune pancreatitis, mediastinal fibrosis and multiple sclerosis.
IgG4, λ recombinant protein is obtained by expression of a phage library in a human cell line and purified by affinity chromatography.

Aplicación

The purified IgG4, λ may be used as an immunoglobulin calibrator, reference antigen, blocking agent, or coating protein in a variety of immunoassays including ELISA, dot blot immunobinding, Western immunobloting, immunodiffusion, immunoelectrophoresis, hemagglutination, and cell binding assays. Purified IgG4, λ was used as isotype control in flow cytometry of chronic lymphocytic leukemia and mantle cell lymphoma cells. It was also used for lectin- surface plasmon resonance and IgG subclass labelling by flow cytometry at a concentration of 50 μg/mL.

Nota de análisis

The purity and identity are determined by immunoelectrophoresis, indirect ELISA, and SDS-PAGE.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Código de clase de almacenamiento: 12 - Non Combustible Liquids
• Clase de riesgo para el agua (WGK): WGK 1
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable