I0654

Interleukin-1 Soluble Receptor, Type I human

>97% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder

• Sinónimos: (IL-1 sRI)
• Número MDL: MFCD01323730
• Código UNSPSC: 51111800
• NACRES: NA.32

Propiedades

• origen biológico: human
• Nivel de calidad: 100
• recombinante: expressed in NSO cells
• Análisis: >97% (SDS-PAGE)
• formulario: lyophilized powder
• mol peso: 36 kDa
• envase: pkg of 0.1 mg
• impurezas: endotoxin, tested
• Nº de acceso UniProt: P14778
• temp. de almacenamiento: −20°C
• Información sobre el gen: human ... IL1R1(3554)

Descripción

Descripción general

Interleukin-1 type 1 receptor (IL1R1) is a glycoprotein. It is mainly expressed on endothelial cells, epithelial cells, hepatocytes, fibroblasts, epidermal dendritic cells as well as T lymphocytes.

Acciones bioquímicas o fisiológicas

Interleukin-1 (IL-1), a cytokine, is a key regulator of acute and chronic inflammation. The IL-1 associated responses are achieved by association of IL-1 with IL-1 type 1 receptor (IL1R1).

Recombinant human IL-1 soluble receptor I is a transmembrane protein and a member of the immunoglobulin superfamily. It is expressed predominantly by T cells, fibroblasts, and endothelial cells.

Forma física

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing 5.0 mg bovine serum albumin

Nota de análisis

The bioactivity is measured by its ability to inhibit the IL-1β-dependent proliferation of a murine helper T cell line, D10.G4.1.

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable