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H9538

Sigma-Aldrich

HNE-DMA

hexane solution, ≥85% (GC)

Sinónimos:

(E)-4-Hydroxynonenal-dimethylacetal, 4-HNE-DMA

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About This Item

Fórmula empírica (notación de Hill):
C11H22O3
Peso molecular:
202.29
Número MDL:
MFCD07370138
Código UNSPSC:
12352200
ID de la sustancia en PubChem:
24724506
NACRES:
NA.77

Nivel de calidad

100

Análisis

≥85% (GC)

formulario

hexane solution

Condiciones de envío

dry ice

temp. de almacenamiento

−20°C

cadena SMILES

CCCCCC(O)\C=C\C(OC)OC

InChI

1S/C11H22O3/c1-4-5-6-7-10(12)8-9-11(13-2)14-3/h8-12H,4-7H2,1-3H3/b9-8+

Clave InChI

ATGIHMSJAARJTF-CMDGGOBGSA-N

Acciones bioquímicas o fisiológicas

Stable form of HNE; toxic second messenger of free radicals.

Nota de preparación

To prepare HNE from HNE-DMA: evaporate the hexane under a gentle stream of nitrogen at room temperature. Working at 4 °C, add 1 ml (5 mg size) or 0.4 ml (2 mg size) of 1 mM cold HCl and stir for 45 minutes, or alternatively, close the vial and shake for 30 minutes. Upon hydrolysis, the initially cloudy solution becomes almost clear. This solution now has a pH of ∼3, contains ∼5 mg (5 mg size) or ∼2 mg (2 mg size) of the aldehyde (HNE), and is stable for at least 24 hours if kept at 4 °C. 6.8 mg HNE-DMA in 1 mL of hexane solution, giving 5 mg of HNE after hydrolysis.It is recommended that the freshly prepared HNE solution be used immediately.

Palabra de señalización

Danger

Clasificaciones de peligro

Aquatic Chronic 2 - Asp. Tox. 1 - Flam. Liq. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Inhalation - STOT SE 3

Órganos de actuación

Central nervous system, Nervous system

Código de clase de almacenamiento

3 - Flammable liquids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

-14.8 °F - closed cup

Punto de inflamabilidad (°C)

-26 °C - closed cup

Equipo de protección personal

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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