H7890

L-Homoserine lactone hydrochloride

suitable for ligand binding assays

• Fórmula empírica (notación de Hill): C₄H₇NO₂ · HCl
• Número de CAS: 2185-02-6
• Peso molecular: 137.56
• Número MDL: MFCD00058172
• Código UNSPSC: 12352209
• ID de la sustancia en PubChem: 24895811
• NACRES: NA.26

Propiedades

• product name: L-Homoserine lactone hydrochloride,
• formulario: powder
• Nivel de calidad: 200
• técnicas: ligand binding assay: suitable
• color: white
• temp. de almacenamiento: −20°C
• cadena SMILES: Cl.N[C@H]1CCOC1=O
• InChI: 1S/C4H7NO2.ClH/c5-3-1-2-7-4(3)6;/h3H,1-2,5H2;1H/t3-;/m0./s1
• Clave InChI: XBKCXPRYTLOQKS-DFWYDOINSA-N

Descripción

Descripción general

L-Homoserine lactone (HSL), also called acyl-HSL, comprises a homoserine lactone ring and a fatty acyl side. The levels of acyl-HSL in bacteria is dictated by the availability of the substrates and acyl-homoserine lactones synthase.

Aplicación

L-Homoserine lactone hydrochloride has been used as an inhibitor for arterial smooth muscle contraction.

Acciones bioquímicas o fisiológicas

L-Homoserine lactone inhibition reduces virulence factors and halts inflammation and tissue damage. In Pseudomonas aeruginosa it controls virulence factor production and biofilm formation. In Agrobacterium tumefaciens, it is essential for conjugal transfer.

Acylated L-Homoserine lactone(s) are used to study bacterial quorum-sensing signaling mechanisms.

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable
• Equipo de protección personal: Eyeshields, Gloves, type N95 (US)