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H1635

Sigma-Aldrich

N-Hippuryl-His-Leu hydrate

chromogenic, ≥98% (HPLC), powder

Sinónimos:

N-Benzoyl-Gly-His-Leu, N-Hippuryl-L-histidyl-L-leucine hydrate

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About This Item

Fórmula empírica (notación de Hill):
C21H27N5O5 · xH2O
Número de CAS:
207386-83-2
Peso molecular:
429.47 (anhydrous basis)
Beilstein:
5664178
Número CE:
250-597-9
Número MDL:
MFCD00149318
Código UNSPSC:
12352204
ID de la sustancia en PubChem:
24895469
NACRES:
NA.32

product name

N-Hippuryl-His-Leu hydrate, powder, ≥98% (HPLC)

Nivel de calidad

200

Análisis

≥98% (HPLC)

formulario

powder

color

white to off-white

solubilidad

acetic acid: ~50 mg/mL

temp. de almacenamiento

−20°C

cadena SMILES

O.CC(C)C[C@H](NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)CNC(=O)c2ccccc2)C(O)=O

InChI

1S/C21H27N5O5.H2O/c1-13(2)8-17(21(30)31)26-20(29)16(9-15-10-22-12-24-15)25-18(27)11-23-19(28)14-6-4-3-5-7-14;/h3-7,10,12-13,16-17H,8-9,11H2,1-2H3,(H,22,24)(H,23,28)(H,25,27)(H,26,29)(H,30,31);1H2/t16-,17-;/m0./s1

Clave InChI

NWOJMNXIJBZMPK-QJHJCNPRSA-N

Información sobre el gen

human ... ACE(1636) , ACE2(59272)
mouse ... ACE3(217246)
rat ... ACE(11421) , ACE2(70008) , ACE3(498012)

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Amino Acid Sequence

NBz-Gly-His-Leu

Aplicación

N-Hippuryl-His-Leu hydrate has been used in the measurement of angiotensin-converting enzyme (ACE) inhibitory activity using oyster hydrolysates, semimembranosus muscle samples, and rabbit lung acetone powder.

Acciones bioquímicas o fisiológicas

N-Hippuryl-His-Leu hydrate (HHL) can be used as an artificial substrate for angiotensin-converting enzyme (ACE).

Sustratos

Substrate for angiotensin converting enzyme.

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Equipo de protección personal

Eyeshields, Gloves, type N95 (US)

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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N Nahariah et al.
Asian-Australasian journal of animal sciences, 28(6), 855-861 (2015-02-27)
Lactobacillus plantarum is used for fermentation of fish products, meat and milk. However, the utilization of these bacteria in egg processing has not been done. This study was designed to evaluate the potential of fermented egg albumen as a functional
Darcy R Flora et al.
Endocrinology, 151(6), 2769-2776 (2010-04-13)
Natriuretic peptide receptor-A (NPR-A), also known as guanylyl cyclase-A, is a transmembrane receptor guanylyl cyclase that is activated by the cardiac hormones atrial natriuretic peptide and B-type natriuretic peptide. Although ligand-dependent NPR-A degradation (also known as down-regulation) is widely acknowledged
A Tiengo et al.
Journal of food science, 74(5), H121-H126 (2009-08-04)
Amaranth seeds have been considered as an excellent alternative or complementary source of food protein due to their balanced amino acid composition. However, their potential as a source of bioactive peptides has not been explored. The present study is aimed
Flávia Giacometti Cavalheiro et al.
Food chemistry, 333, 127482-127482 (2020-07-14)
In order to evaluate differences in the peptide profile and bioactive potential in dairy products, by increasing the protein content and using proteolytic bacteria strain to enable the release of bioactive peptides, a high-protein yogurt with adjunct culture was developed.
Anna Iwaniak et al.
International journal of molecular sciences, 22(6) (2021-04-04)
In silico and in vitro methods were used to analyze ACE- and DPP-IV-inhibiting potential of Gouda cheese with a modified content of β-casein. Firstly, the BIOPEP-UWM database was used to predict the presence of ACE and DPP-IV inhibitors in casein
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