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Merck

H0377

Sigma-Aldrich

DL-5-Hydroxylysine hydrochloride

≥98% (TLC)

Sinónimos:

2,6-Diamino-5-hydroxycaproic acid hydrochloride, 2,6-Diamino-5-hydroxyhexanoic acid hydrochloride

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About This Item

Fórmula lineal:
NH2CH2CH(OH)CH2CH2CH(NH2)COOH · HCl
Número de CAS:
Peso molecular:
198.65
Beilstein:
3914368
Número CE:
Número MDL:
Código UNSPSC:
12352209
ID de la sustancia en PubChem:
NACRES:
NA.26

product name

DL-5-Hydroxylysine hydrochloride,

Análisis

≥98% (TLC)

Nivel de calidad

formulario

powder

color

white

mp

225 °C (dec.) (lit.)

aplicaciones

detection
peptide synthesis

cadena SMILES

Cl.NCC(O)CCC(N)C(O)=O

InChI

1S/C6H14N2O3.ClH/c7-3-4(9)1-2-5(8)6(10)11;/h4-5,9H,1-3,7-8H2,(H,10,11);1H

Clave InChI

MJXVOTKVFFAZQJ-UHFFFAOYSA-N

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Aplicación


  • Characterization of acetyl-CoA: L-lysine N6-acetyltransferase, which catalyses the first step of carbon catabolism from lysine in Saccharomyces cerevisiae.: This research investigates the enzyme acetyl-CoA: L-lysine N6-acetyltransferase, which initiates the catabolism of lysine in Saccharomyces cerevisiae. Utilizing DL-5-Hydroxylysine hydrochloride, the study provides insights into the metabolic pathways and regulatory mechanisms of lysine degradation, contributing to the broader understanding of amino acid metabolism in yeast (Bode et al., 1993).

Acciones bioquímicas o fisiológicas

DL-5-Hydroxylysine is a racemic mixture of D- and L- enantiomers of 5-hydroxylysine which may be used as potential target markers for radical-induced protein oxidation.

Otras notas

Mixed DL and DL-allo

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Equipo de protección personal

Eyeshields, Gloves, type N95 (US)


Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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R Bode et al.
Archives of microbiology, 160(5), 397-400 (1993-01-01)
The carbon catabolism of L-lysine starts in Saccharomyces cerevisiae with acetylation by an acetyl-CoA:L-lysine N6-acetyltransferase. The enzyme is strongly induced in cells grown on L-lysine as sole carbon source and has been purified about 530-fold. Its activity was specific for
B Morin et al.
Chemical research in toxicology, 11(11), 1265-1273 (1998-11-17)
gamma-Irradiation of several amino acids (Val, Leu, Ile, Lys, Pro, and Glu) in the presence of O2 generates hydroperoxides. We have previously isolated and characterized valine and leucine hydroperoxides, and hydroxides, and have detected these products in both isolated systems
M Droux et al.
Archives of biochemistry and biophysics, 316(1), 585-595 (1995-01-10)
Cystathionine beta-lyase, the second enzyme of the transsulfuration pathway leading to homocysteine synthesis was purified over 16,000-fold from spinach (Spinacia oleracea L.) leaf chloroplasts (soluble fraction). Enzyme activity was followed along the purification scheme by either a colorimetric method for
N Zhang et al.
International journal of plant sciences, 160(3), 511-519 (2001-09-07)
Lactuca sativa cv. Baijianye seedlings do not normally produce lateral roots, but removal of the root tip or application of auxin, especially indole-butyric acid, triggered the formation of lateral roots. Primordia initiated within 9 h and were fully developed after
Lasanthi P Jayathilaka et al.
Organic letters, 6(21), 3659-3662 (2004-10-08)
[reaction: see text] L-alpha-(1-Cyclobutenyl)glycine (1-Cbg) was targeted as a potentially translatable analogue of isoleucine and valine and as a useful building block for peptides. An enantioselective synthesis was executed in which the key step was diastereoselective addition of 1-cyclobutenylmagnesium bromide

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