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Merck

GW21442

Sigma-Aldrich

Anti-DPP4 antibody produced in chicken

affinity isolated antibody, buffered aqueous solution

Sinónimos:

Anti-CD26, Anti-Dipeptidyl peptidase 4

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About This Item

Número MDL:
Código UNSPSC:
12352203
NACRES:
NA.41

origen biológico

chicken

Nivel de calidad

conjugado

unconjugated

forma del anticuerpo

affinity isolated antibody

tipo de anticuerpo

primary antibodies

clon

polyclonal

formulario

buffered aqueous solution

reactividad de especies

rat, mouse, human

fabricante / nombre comercial

Genway 15-288-21442

técnicas

immunocytochemistry: suitable
western blot: suitable

Nº de acceso NCBI

Nº de acceso UniProt

Condiciones de envío

wet ice

temp. de almacenamiento

−20°C

modificación del objetivo postraduccional

unmodified

Información sobre el gen

human ... DPP4(1803)

Descripción general

Dipeptidyl peptidase-4 (DPP4) is a serine type protease is also known as CD26 or adenosine deaminase binding protein. It is expressed in the plasma membranes of T cells and activated natural killer or B cells. Its expressions also have been found on a number of endothelial and differentiated epithelial cells.

Inmunógeno

Immunogen Sequence: GI # 4503367, sequence 547-610
Recombinant dipeptidylpeptidase IV (CD26, adenosine deaminase complexing protein 2)

Aplicación

Anti-DPP4 antibody produced in chicken is suitable for immunocytochemistry and western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

Acciones bioquímicas o fisiológicas

Dipeptidyl peptidase-4 (DPP4) is a protein encoded by the DPP4 gene in humans. The T cell activation molecule DPP4 is associated with a 43kDa protein. It is associated with multiple sclerosis (MS) pathophysiology. DPP4 interacts on the T cell surface along with adenosine deaminase (ADA). Mutation in DPP4 causes an X-linked Simpson-Golabi-Behmel syndrome.

Forma física

Solution in phosphate buffered saline containing 0.02% sodium azide.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Código de clase de almacenamiento

10 - Combustible liquids

Clase de riesgo para el agua (WGK)

WGK 1

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Equipo de protección personal

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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C Durinx et al.
European journal of biochemistry, 267(17), 5608-5613 (2000-08-22)
Dipeptidyl peptidase IV (DPPIV, EC 3.4.14.5) is a serine type protease with an important modulatory activity on a number of chemokines, neuropeptides and peptide hormones. It is also known as CD26 or adenosine deaminase (ADA; EC 3.5.4.4) binding protein. DPPIV
J Kameoka et al.
Science (New York, N.Y.), 261(5120), 466-469 (1993-07-23)
CD26, the T cell activation molecule dipeptidyl peptidase IV (DPPIV), associates with a 43-kilodalton protein. Amino acid sequence analysis and immunoprecipitation studies demonstrated that this 43-kilodalton protein was adenosine deaminase (ADA). ADA was coexpressed with CD26 on the Jurkat T
Jamshid Davoodi et al.
Proteomics, 7(13), 2300-2310 (2007-06-06)
Simpson-Golabi-Behmel syndrome (SGBS) is an X-linked condition shown to be the result of deletions of the glypican-3 (GPC3) gene. GPC3 is a proteoglycan localized to the cell membrane via a glycosylphosphatidyl-inositol (GPI) anchor. To further elucidate the GPC3 function(s), we
Marta Tejera-Alhambra et al.
Clinical immunology (Orlando, Fla.), 150(2), 170-183 (2014-01-15)
Multiple sclerosis (MS) is a prototypic Th1/Th17 chronic autoimmune disease of the central nervous system. Dipeptidyl peptidase 4 (DPP4 or CD26) is a multifunctional molecule involved in autoimmune diseases' pathophysiology. We sought to integrate disparate pieces of data and analyze
Cuiqing Ma et al.
Vaccine, 32(46), 6170-6176 (2014-09-23)
The newly emerged Middle East respiratory syndrome coronavirus (MERS-CoV) is currently spreading among humans, making development of effective MERS vaccines a high priority. A defined receptor-binding domain (RBD) in MERS-CoV spike protein can potentially serve as a subunit vaccine candidate

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