GE17-5481-51

HiTrap^® Capto^™ Core 700

Cytiva 17-5481-51, pack of 5 × 1 mL

• Sinónimos: Capto Core 700 Column
• Código UNSPSC: 23151817
• NACRES: NA.56

Propiedades

• ligand: octylamine
• envase: pack of 5 × 1 mL
• fabricante / nombre comercial: Cytiva 17-5481-51
• Parámetros: 5 bar
• columna D.I.: 7 mm
• matriz: highly cross-linked agarose
• tam. prom. pieza: 75 (d₅₀v is the median particle size of the cumulative volume distribution)
• cleaning: 3-14(pH interval where the medium can be subjected to, for cleaning- or sanitization-in-place.)
• working range: 2-14(pH interval where the medium can be operated without significant change in function.)
• capacidad: ~13 mg binding capacity (ovalbumin)
• idoneidad: suitable for bioprocess medium

Descripción

Descripción general

Dynamic binding capacities were measured at 10% breakthrough with a residence time of 3 min (1.6 ml/min = 200 cm/h) in HiScreen columns. Buffer: 20 mM Tris-HCl, 150 mM NaCl, pH 7.5.

HiTrap Capto Core 700 is prepacked with Capto Core 700, a multimodal BioProcess resin for intermediate purification and polishing of viruses and other large biomolecules. Capto Core 700 is a novel, layered bead chromatography resin consisting of a porous outer layer and ligand-activated core. The octylamine ligands found in the core of the beads are multimodal, being both hydrophobic and positively charged. These internalized ligands bind impurities strongly over a wide range of pH and salt concentration. The pores of the bead outer layer prevent large targets (Mr > 700 000) from binding to the ligands while smaller impurities can enter freely into the beads where they are captured.

Características y beneficios

• High capacity and productivity in flowthrough mode.
• Prepacked HiTrap columns for easy screening and convenient process development, as well as small scale purification.
• Wide operational window of pH and conductivity.

Almacenamiento y estabilidad

Please be aware this product may be shipped 90 days before the expiration date. For more information on the batch specific expiration date, please contact technical service.

Store at 4 to 30 °C (20% Ethanol)

Nota de análisis

To view the Certificate of Analysis for this product, please visit www.cytiva.com.

Información legal

Capto is a trademark of Cytiva

HiTrap is a registered trademark of Cytiva

Información de seguridad

• Pictogramas: GHS02
• Palabra de señalización: Warning
• Frases de peligro: H226
• Consejos de prudencia: P280 - P210 - P241 - P235 - P303 + P361 + P353 - P501
• Código de clase de almacenamiento: 3 - Flammable liquids