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G7000

Sigma-Aldrich

α-D-Glucose 1-phosphate disodium salt hydrate

≥97% (Enzymatic Purity, anhydrous)

Sinónimos:

α-D-Glucopyranose 1-phosphate, Cori ester

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About This Item

Fórmula lineal:
C6H11O9PNa2 · xH2O
Número de CAS:
56401-20-8
Peso molecular:
304.10 (anhydrous basis)
Número CE:
260-154-1
Número MDL:
MFCD00150837
Código UNSPSC:
12352201
ID de la sustancia en PubChem:
24895281
NACRES:
NA.25

origen biológico

synthetic

Nivel de calidad

200

Análisis

≥97% (Enzymatic Purity, anhydrous)

formulario

powder

impurezas

≤0.1 mol % glucose
≤0.5 mol % α-D-glucose 1,6-diphosphate

color

white

solubilidad

water: 50 mg/mL, clear, colorless

trazas de catión

Na: 13.5-16.7% (anhydrous)

aplicaciones

agriculture

temp. de almacenamiento

−20°C

cadena SMILES

[Na+].[Na+].[H]O[H].OC[C@H]1O[C@H](OP([O-])([O-])=O)[C@H](O)[C@@H](O)[C@@H]1O

InChI

1S/C6H13O9P.2Na.H2O/c7-1-2-3(8)4(9)5(10)6(14-2)15-16(11,12)13;;;/h2-10H,1H2,(H2,11,12,13);;;1H2/q;2*+1;/p-2/t2-,3-,4+,5-,6-;;;/m1.../s1

Clave InChI

YWAUQXHOCBBYLP-FBNUBEQJSA-L

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Descripción general

α-D-Glucose 1-phosphate is converted into D-glucose-6-phosphate by the enzyme phosphoglucomutase.

Acciones bioquímicas o fisiológicas

Glucose-1-phosphate (G1P) is produced from glycogen during glycogenolysis by the actions of glycogen phosphorylase. Conversion to glucose-6-phosphate (G6P) by phosphoglucomutase allows for entry of the glucose molecule into metabolic pathways such as glycolysis. During glycogenesis, G6P is converted to G1P by the actions of phosphoglucose isomerase.

Nota de preparación

Prepared by a modification of the procedure of McCready, R.M., et al., J. Am. Chem. Soc., 66, 560 (1944).

Otras notas

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Equipo de protección personal

Eyeshields, Gloves, type N95 (US)

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Kyra-Melinda Alexacou et al.
Bioorganic & medicinal chemistry, 18(22), 7911-7922 (2010-10-16)
Glycogen phosphorylase (GP) is a promising target for the treatment of type 2 diabetes. In the process of structure based drug design for GP, a group of 15 aromatic aldehyde 4-(β-d-glucopyranosyl)thiosemicarbazones have been synthesized and evaluated as inhibitors of rabbit
Ting Yang et al.
The Biochemical journal, 429(3), 533-543 (2010-05-21)
The diverse types of glycoconjugates synthesized by trypanosomatid parasites are unique compared with the host cells. These glycans are required for the parasite survival, invasion or evasion of the host immune system. Synthesis of those glycoconjugates requires a constant supply
Jef Van der Borght et al.
Biotechnology journal, 5(9), 986-993 (2010-08-28)
β-D-Glucose-1-phosphate (βGlc1P) is an efficient glucosyl donor for both enzymatic and chemical glycosylation reactions but is currently very costly and not available in large amounts. This article provides an efficient production method of βGlc1P from trehalose and phosphate using the
Cátia Nunes et al.
Plant physiology and biochemistry : PPB, 63, 89-98 (2012-12-22)
SnRK1 of the SNF1/AMPK group of protein kinases is an important regulatory protein kinase in plants. SnRK1 was recently shown as a target of the sugar signal, trehalose 6-phosphate (T6P). Glucose 6-phosphate (G6P) can also inhibit SnRK1 and given the
Rickard Olsson et al.
Langmuir : the ACS journal of surfaces and colloids, 26(24), 18760-18770 (2010-11-20)
Adsorption, desorption, and precipitation reactions at environmental interfaces govern the fate of phosphorus in terrestrial and aquatic environments. Typically, a substantial part of the total pool of phosphorus consists of organophosphate, and in this study we have focused on the
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