G6752

Guanosine

≥98%

• Sinónimos: 9-(β-D-Ribofuranosyl)guanine, Guanine-9-β-D-ribofuranoside
• Fórmula empírica (notación de Hill): C₁₀H₁₃N₅O₅
• Número de CAS: 118-00-3
• Peso molecular: 283.24
• Beilstein: 625911
• Número CE: 204-227-8
• Número MDL: MFCD00010182
• Código UNSPSC: 41106305
• ID de la sustancia en PubChem: 24895268
• NACRES: NA.51

Propiedades

• origen biológico: microbial
• Nivel de calidad: 100
• Análisis: ≥98%
• formulario: powder
• mp: 250 °C (dec.) (lit.)
• solubilidad: formic acid:water (1:1): 50 mg/mL, clear to very slightly hazy, colorless to faintly yellow
• cadena SMILES: [H]O[H].NC1=Nc2c(ncn2[C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)C(=O)N1
• InChI: 1S/C10H13N5O5/c11-10-13-7-4(8(19)14-10)12-2-15(7)9-6(18)5(17)3(1-16)20-9/h2-3,5-6,9,16-18H,1H2,(H3,11,13,14,19)/t3-,5-,6-,9-/m1/s1
• Clave InChI: NYHBQMYGNKIUIF-UUOKFMHZSA-N

Descripción

Descripción general

Guanosine is an aromatic organic molecule and a purine nucleoside. It is present in the cerebrospinal fluid, intestinal cells, blood-brain barrier and in brain microvessels.

Aplicación

Guanosine has been used:

• as a reference standard for the analysis of glucosinolates by high-performance liquid chromatography with diode-array detection and electrospray ionization tandem mass spectrometry (HPLC-DAD-ESI/MS)
• as a component of Mouse Embryonic Fibroblasts (MEFs) culture
• as a standard for the detection of residual RNA contaminant in oil palm plant genome samples by HPLC

Acciones bioquímicas o fisiológicas

Guanosine nucleoside elicits cellular effect as the guanine-based purinergic system. It modulates glutamate uptake by glutamate transporters. It may have neuroprotective functionality in central nervous system disorders. Guanosine promotes neurite arborization, outgrowth, proliferation and differentiation. Administration of guanosine replenished GTP and elicits protective function in renal ischemic injury.

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 2
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable
• Equipo de protección personal: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges